Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 7/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL466296 | 0.74 | KDM4E (0.54) | SIRT1BCAT2KDM4EALDH1A1MAPT | |
| SCHEMBL10909866 | 0.73 | KDM4E (0.41) | BCAT2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL402013 | 0.71 | BCAT2 (0.56) | SIRT1BCAT2KDM4EALDH1A1MAPT | |
| SCHEMBL1135187 | 0.70 | ALDH1A1 (0.52) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL11215370 | 0.70 | ALDH1A1 (0.45) | SIRT1BCAT2KDM4EALDH1A1MAPT | |
| SCHEMBL6066755 | 0.69 | KDM4E (0.48) | SIRT1BCAT2KDM4EALDH1A1MAPT | |
| SCHEMBL11184702 | 0.68 | CA2 (0.47) | SIRT1KDM4EMAPTHPGDGAA | |
| SCHEMBL16925206 | 0.68 | SIRT1 (0.41) | SIRT1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL10883264 | 0.67 | SIRT1 (0.38) | SIRT1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7093585 | 0.67 | ALDH1A1 (0.50) | SIRT1BCAT2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010019649-A2 | ACTIVE POLYMER COMPOSITIONS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-02-18 | — | — | WO | disclosed |