Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 7/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | STAMBP | O95630 | 1/20 | 0.35 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418361 | 0.76 | SIRT1 (0.60) | SIRT1PARP1TSHRMAPTHSD17B10 | |
| SCHEMBL320037 | 0.69 | ALDH1A1 (0.61) | PARP1TSHRMAPTHSD17B10POLB | |
| SCHEMBL9710493 | 0.68 | EPHB4 (0.40) | SIRT1PARP1TSHRMAPTHSD17B10 | |
| SCHEMBL3475642 | 0.67 | SIRT1 (0.42) | SIRT1PARP1TSHRMAPTHSD17B10 | |
| SCHEMBL11455512 | 0.67 | POLB (0.37) | MAPTHSD17B10POLBALDH1A1KMT2A | |
| SCHEMBL29008206 | 0.67 | ALDH1A1 (0.58) | PARP1TSHRMAPTHSD17B10POLB | |
| SCHEMBL10994984 | 0.66 | PPIA (0.47) | PARP1MAPTTDP1KDM4EPBRM1 | |
| SCHEMBL1613338 | 0.65 | MMP2 (0.43) | PARP1TSHRMAPTHSD17B10POLB | |
| SCHEMBL466296 | 0.65 | KDM4E (0.54) | SIRT1PARP1TSHRMAPTHSD17B10 | |
| SCHEMBL1668962 | 0.65 | CA2 (0.59) | PARP1TSHRMAPTHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0100448-B1 | LIQUID, ACTIVE AGENT FORMULATIONS AND THEIR USE IN PREPARING MICRO-EMULSIONS | A. Nattermann & Cie. GmbH (DE) | 1986-08-27 | — | — | EP | disclosed |
| EP-0082437-B1 | PESTICIDAL SUSPENSION CONCENTRATES | A. Nattermann & Cie. GmbH (DE) | 1986-05-07 | — | — | EP | disclosed |
| US-4567161-A | Liquid active ingredient concentrates for preparation of microemulsions | A. NATTERMAN & CIE GMBH (DE) | 1986-01-28 | — | — | US | disclosed |
| EP-0100448-A1 | Liquid, active agent formulations and their use in preparing micro-emulsions | A. Nattermann & Cie. GmbH (DE) | 1984-02-15 | — | — | EP | disclosed |
| EP-0082437-A2 | Pesticidal suspension concentrates | A. Nattermann & Cie. GmbH (DE) | 1983-06-29 | — | — | EP | disclosed |