Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.39 |
| ▸ | EEF2K | O00418 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL740648 | 0.81 | SLC22A12 (0.41) | KMT2ASLC22A12EEF2KTP53THRB | |
| SCHEMBL3474951 | 0.69 | KMT2A (0.76) | KMT2A | |
| SCHEMBL15875920 | 0.63 | KMT2A (0.60) | KMT2A | |
| SCHEMBL99447 | 0.62 | KMT2A (0.61) | KMT2AEEF2K | |
| SCHEMBL14926951 | 0.61 | ALDH1A1 (0.40) | KMT2ATP53 | |
| SCHEMBL3477086 | 0.61 | ALDH1A1 (0.37) | KMT2AMEN1LMNA | |
| SCHEMBL739438 | 0.61 | ALDH1A1 (0.47) | KMT2ALMNA | |
| SCHEMBL132834 | 0.59 | KMT2A (0.84) | KMT2A | |
| SCHEMBL741117 | 0.58 | ALDH1A1 (0.36) | KMT2ATHRBMEN1LMNA | |
| SCHEMBL741438 | 0.57 | ALDH1A1 (0.47) | KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010130842-A1 | THIENO [2, 3-B] PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2010-11-18 | — | — | WO | disclosed |