SCHEMBL3475797

SCHEMBL3475797

COC(=O)NCCC[Si](C)(OC)OC

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.53
ACHE P22303 11/20 0.39
TDP1 Q9NUW8 1/20 0.35
TSHR P16473 1/20 0.34
BCHE P06276 1/20 0.34
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5916512 0.92 EPHX1 (0.60) EPHX1ACHETDP1
SCHEMBL8502808 0.92 EPHX1 (0.60) EPHX1ACHETDP1
SCHEMBL5916524 0.87 EPHX1 (0.47) EPHX1ACHETSHRBCHEMEN1
SCHEMBL16412053 0.85 EPHX1 (0.45) EPHX1TDP1TSHRMEN1KMT2A
SCHEMBL30358659 0.85 ACHE (0.47) EPHX1ACHEKMT2A
SCHEMBL9189818 0.83 TDP1 (0.57) EPHX1TDP1TSHRMEN1GAA
SCHEMBL960399 0.83 KDM4E (0.54) TSHR
SCHEMBL3476350 0.83 EPHX1 (0.53) EPHX1ACHETDP1TSHRBCHE
SCHEMBL16613121 0.83 EPHX1 (0.35) EPHX1ACHETDP1TSHRMEN1
SCHEMBL8503562 0.83 EPHX1 (0.57) EPHX1ACHETDP1TSHRBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937697-B1 METHOD FOR PRODUCTION OF ISOCYANATOSILANES MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-16 EP claimed
US-20130079449-A1 Polymer Composition and Method SOLVAY SA (BE) 2013-03-28 US claimed
WO-2013043321-A1 POLYMER COMPOSITION AND METHOD CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2013-03-28 WO claimed
US-7825243-B2 Process for the production of isocyanatosilane and silylisocyanurate MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-11-02 US claimed
EP-1869058-B1 PROCESS FOR MAKING SILYLISOCYANURATE MOMENTIVE PERFORMANCE MAT INC (US) 2009-12-16 EP claimed
EP-1885731-B1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE MOMENTIVE PERFORMANCE MAT INC (US) 2009-11-11 EP claimed
EP-1937697-A2 METHOD FOR PRODUCTION OF ISOCYANATOSILANES Momentive Performance Materials Inc. (US) 2008-07-02 EP claimed
EP-1885731-A1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE Momentive Performance Materials Inc. (US) 2008-02-13 EP claimed
EP-1869058-A2 PROCESS FOR MAKING SILYLISOCYANURATE General Electric Company (US) 2007-12-26 EP claimed
WO-2007037817-A2 METHOD FOR PRODUCTION OF ISOCYANATOSILANES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2007-04-05 WO claimed
WO-2006132799-A1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2006-12-14 WO claimed
US-20060276644-A1 Process for the production of isocyanatosilane and silylisocyanurate GENERAL ELECTRIC COMPANY 2006-12-07 US claimed
WO-2006113182-A2 PROCESS FOR MAKING SILYLISOCYANURATE GENERAL ELECTRIC COMPANY (US) 2006-10-26 WO claimed
US-20060235221-A1 Process for making silylisocyanurate MOMENTIVE PERFORMANCE MATERIALS INC. 2006-10-19 US claimed
US-7060849-B1 Method for production of isocyanatosilanes GENERAL ELECTRIC COMPANY (US) 2006-06-13 US claimed
CN-112062786-A Method for purifying isocyanate silane coupling agent and isocyanate silane coupling agent 江苏华盛锂电材料股份有限公司 2020-12-11 CN disclosed
EP-3221324-B1 PRODUCTION OF ISOCYANATE FUNCTIONAL ORGANOSILANES WACKER CHEMIE AG (DE) 2019-05-01 EP disclosed
EP-0864574-A2 Process for producing silicon-containing isocyanate compound TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-09-16 EP disclosed
EP-0649850-A1 Process for making isocyanatoorganosilanes OSi Specialties, Inc. (US) 1995-04-26 EP disclosed
US-5393910-A Process for making isocyanatoorganosilanes OSI SPECIALTIES, INC. (US) 1995-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235221-A1 Process for making silylisocyanurate PCMT1, SRM, STOM EPHX1 4442/4885ACHE 1265/4885TDP1 4596/4885
US-20060276644-A1 Process for the production of isocyanatosilane and silylisocyanurate SI, TST, PCMT1 EPHX1 4685/4885ACHE 1637/4885TDP1 4726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.