Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MGMT | P16455 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11788910 | 0.86 | CYP19A1 (0.39) | MAPTCYP19A1CYP11B1CYP11B2HTT | |
| SCHEMBL3476385 | 0.82 | HTR2A (0.41) | MAPTHTTMGMTLMNAHPGD | |
| SCHEMBL11776775 | 0.79 | CYP19A1 (0.49) | MAPTCYP19A1CYP11B1CYP11B2LMNA | |
| SCHEMBL29434631 | 0.77 | TSHR (0.44) | MAPTCYP19A1CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL27606253 | 0.75 | BCL2 (0.47) | HPGDMEN1KMT2A | |
| SCHEMBL8564450 | 0.75 | MAPT (0.41) | MAPTCYP19A1CYP11B1CYP11B2HTT | |
| SCHEMBL8568481 | 0.75 | HTT (0.50) | MAPTCYP19A1CYP11B1CYP11B2HTT | |
| SCHEMBL31257130 | 0.75 | CALM1 (0.46) | HPGDALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL17242668 | 0.74 | MAPK1 (0.41) | MAPTLMNAALDH1A1SMN1; SMN2KDM4E | |
| Aniline SCHEMBL10525035 | 0.74 | ALDH1A1 (0.47) | MAPTLMNAALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1018508-B1 | Cationic monobenzenic nitrophenylene diamines, their use for dyeing keratinic fibres, dye compositions containing them and dye processes | OREAL (FR) | 2005-05-04 | — | — | EP | disclosed |
| EP-1018508-A1 | Cationic monobenzenic nitrophenylene diamines, their use for dyeing keratinic fibres, dye compositions containing them and dye processes | L'OREAL (FR) | 2000-07-12 | — | — | EP | disclosed |