Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MGMT | P16455 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476385 | 0.80 | HTR2A (0.41) | MAPTHTTMGMTLMNAHPGD | |
| SCHEMBL8564427 | 0.76 | ALDH1A1 (0.38) | MAPTHTTMGMTLMNAHPGD | |
| SCHEMBL8566312 | 0.75 | MAPT (0.53) | MAPTHTTLMNAHPGDMAPK1 | |
| SCHEMBL8566919 | 0.75 | MGMT (0.53) | MAPTHTTMGMTCYP19A1CYP11B1 | |
| SCHEMBL8568938 | 0.75 | GSTP1 (0.49) | MAPTHTTMGMTLMNAHPGD | |
| SCHEMBL6155901 | 0.75 | MAPT (0.40) | MAPTHTTMGMTLMNAHPGD | |
| SCHEMBL28238100 | 0.75 | HTT (0.49) | MAPTHTTMGMTLMNAHPGD | |
| SCHEMBL8562255 | 0.74 | ALDH1A1 (0.51) | MAPTHTTMGMTLMNAHPGD | |
| SCHEMBL8568707 | 0.74 | CES2 (0.39) | MAPTHTTMGMTLMNAALDH1A1 | |
| SCHEMBL8566844 | 0.74 | MEN1 (0.40) | MAPTHTTLMNAHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |