Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 4/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3474913 | 0.78 | FAAH (0.58) | MAPTFAAH | |
| SCHEMBL3476685 | 0.78 | FAAH (0.59) | MAPTKDM4EMEN1TSHRKMT2A | |
| SCHEMBL3476078 | 0.76 | FAAH (0.46) | FAAH | |
| SCHEMBL3476242 | 0.74 | FAAH (0.44) | FAAH | |
| SCHEMBL13436639 | 0.66 | FAAH (0.57) | FAAH | |
| SCHEMBL30611175 | 0.65 | FAAH (0.55) | PTGESMAPTFAAH | |
| SCHEMBL21154032 | 0.65 | FAAH (0.55) | PTGESMAPTFAAH | |
| SCHEMBL20334924 | 0.63 | PTGES (0.39) | PTGESMAPTKDM4EMEN1KMT2A | |
| SCHEMBL30190038 | 0.62 | RAB9A (0.59) | MAPTKDM4EMEN1TSHRKMT2A | |
| SCHEMBL1550272 | 0.62 | RAB9A (0.59) | MAPTKDM4EMEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |