Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 12/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAK | O14976 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476685 | 0.84 | FAAH (0.59) | FAAHMAPT | |
| SCHEMBL3477385 | 0.82 | FAAH (0.58) | FAAH | |
| SCHEMBL3476242 | 0.78 | FAAH (0.44) | FAAH | |
| SCHEMBL3476542 | 0.78 | PTGES (0.33) | FAAHMAPT | |
| SCHEMBL3476078 | 0.77 | FAAH (0.46) | FAAH | |
| SCHEMBL13436711 | 0.74 | FAAH (1.00) | FAAHHRH3 | |
| SCHEMBL3475486 | 0.64 | FAAH (0.69) | FAAHHRH3IRAK4AAK1 | |
| SCHEMBL30626327 | 0.63 | LOX (0.55) | FAAHMAPTCHRNA7AAK1S1PR1 | |
| SCHEMBL16116782 | 0.63 | LOX (0.55) | FAAHMAPTCHRNA7AAK1S1PR1 | |
| SCHEMBL3391926 | 0.61 | AAK1 (0.48) | FAAHIRAK4CHRNA7AAK1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |