Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 15/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3474913 | 0.77 | FAAH (0.58) | FAAH | |
| SCHEMBL3477385 | 0.77 | FAAH (0.58) | FAAH | |
| SCHEMBL3476685 | 0.77 | FAAH (0.59) | FAAH | |
| SCHEMBL3476542 | 0.76 | PTGES (0.33) | FAAH | |
| SCHEMBL13436715 | 0.74 | FAAH (0.57) | FAAHJAK1 | |
| SCHEMBL3476242 | 0.73 | FAAH (0.44) | FAAH | |
| SCHEMBL3476570 | 0.63 | FAAH (1.00) | FAAH | |
| SCHEMBL5832003 | 0.62 | KDM6B (0.52) | FAAH | |
| SCHEMBL13436692 | 0.57 | FAAH (0.60) | FAAH | |
| SCHEMBL28104788 | 0.56 | ALOX5 (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |