Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | USP2 | O75604 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718845 | 0.73 | RAB9A (0.60) | ALDH1A1RAB9ANPC1GAAPKM | |
| SCHEMBL21776904 | 0.69 | NPC1 (0.58) | ALDH1A1RAB9ANPC1GAAPKM | |
| SCHEMBL8567637 | 0.69 | RAB9A (0.58) | ALDH1A1RAB9ANPC1GAAPKM | |
| SCHEMBL1005268 | 0.66 | NPC1 (0.54) | ALDH1A1RAB9ANPC1GAAPKM | |
| SCHEMBL31213015 | 0.66 | ALDH1A1 (0.54) | ALDH1A1RAB9ANPC1GAAPKM | |
| SCHEMBL2658434 | 0.64 | NPC1 (1.00) | ALDH1A1RAB9ANPC1GAAPKM | |
| SCHEMBL1003521 | 0.63 | TOP2A (0.58) | ALDH1A1RAB9ANPC1GAAPKM | |
| SCHEMBL11374592 | 0.62 | RAB9A (0.81) | ALDH1A1RAB9ANPC1GAAPKM | |
| SCHEMBL5781695 | 0.61 | IMPDH2 (0.48) | ALDH1A1CLK4MEN1USP2KMT2A | |
| SCHEMBL3475836 | 0.60 | NPC1 (0.56) | ALDH1A1RAB9ANPC1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |