Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21776904 | 0.82 | NPC1 (0.58) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL8567637 | 0.82 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL1005268 | 0.78 | NPC1 (0.54) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL31213015 | 0.78 | ALDH1A1 (0.54) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL2658434 | 0.75 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL6929444 | 0.75 | F2 (0.83) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL1003521 | 0.74 | TOP2A (0.58) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL3477331 | 0.73 | ALDH1A1 (0.45) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL3322328 | 0.73 | PSEN1 (0.39) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL16004922 | 0.71 | MEN1 (0.46) | RAB9ANPC1SMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151472-A | Dissolving polyetherimides in a solvent, adding a dianhydride and a diamine, reacting to form a polyamic acid and cyclizing to form a polyimide | GENERAL DYNAMICS CORPORATION, CONVAIR DIVISION (US) | 1992-09-29 | — | — | US | disclosed |