SCHEMBL3477951

SCHEMBL3477951

CC(CC(N)=O)CC(=O)N(C)C

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 2/20 0.36
CHRNB4 P30926 2/20 0.36
CHRNA4 P43681 2/20 0.36
ALDH1A1 P00352 1/20 0.33
CHRNA3 P32297 1/20 0.31
ECE1 P42892 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14166969 1.00 CHRNB2 (0.36) CHRNB2CHRNB4CHRNA4ALDH1A1CHRNA3
SCHEMBL14655206 1.00 CHRNB2 (0.36) CHRNB2CHRNB4CHRNA4ALDH1A1CHRNA3
SCHEMBL3392036 0.83 ALDH1A1 (0.38) ALDH1A1ECE1TDP1
SCHEMBL7360452 0.79 FAAH (0.32) CHRNB2CHRNB4CHRNA4CHRNA3
SCHEMBL5325220 0.79 CHRNB2 (0.38) CHRNB2CHRNB4CHRNA4ALDH1A1TDP1
SCHEMBL13382215 0.79 ALDH1A1 (0.46) CHRNB2CHRNB4CHRNA4ALDH1A1TDP1
Acetamide SCHEMBL4103797 0.78 LMNA (0.47) ALDH1A1ECE1TDP1
SCHEMBL15810278 0.77 CHRNB2 (0.37) CHRNB2CHRNB4CHRNA4ALDH1A1
SCHEMBL10175210 0.76 CHRNB2 (0.39) CHRNB2CHRNB4CHRNA4ALDH1A1TDP1
SCHEMBL14671182 0.76 ALDH1A1 (0.41) CHRNB2CHRNB4CHRNA4ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1566417-B1 COMPOSITION FOR POROUS FILM FORMATION, POROUS FILM, PROCESS FOR PRODUCING THE SAME, INTERLAYER INSULATION FILM AND SEMICONDUCTOR DEVICE PANASONIC CORP (JP) 2010-03-24 EP disclosed
US-20070087124-A1 COMPOSITION FOR FORMING POROUS FILM, POROUS FILM AND METHOD FOR FORMING THE SAME, INTERLEVEL INSULATOR FILM, AND SEMICONDUCTOR DEVICE MATSUSHITA ELECTRIC INDUSTRIAL CO. LTD. (JP) 2007-04-19 US disclosed
US-7148198-B2 Antibacterial agents BRITISH BIOTECH PHARMACEUTICALS, LTD. (GB) 2006-12-12 US disclosed
US-7126208-B2 Composition for forming porous film, porous film and method for forming the same, interlevel insulator film, and semiconductor device MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2006-10-24 US disclosed
EP-1566417-A1 COMPOSITION FOR POROUS FILM FORMATION, POROUS FILM, PROCESS FOR PRODUCING THE SAME, INTERLAYER INSULATION FILM AND SEMICONDUCTOR DEVICE MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2005-08-24 EP disclosed
US-6930393-B2 hydrolyzable silicon compound or at least one product resulting from at least partial hydrolysis condensation of the silicon compound SHIN-ETSU CHEMICAL CO. LTD. (JP) 2005-08-16 US disclosed
US-20050014702-A1 Antibacterial agents BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) 2005-01-20 US disclosed
US-20040232553-A1 Composition for forming porous film, porous film and method for forming the same, interlevel insulator film, and semiconductor device MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. 2004-11-25 US disclosed
US-20040195660-A1 Composition for forming porous film, porous film and method for forming the same, interlayer insulator film, and semiconductor device SHIN-ETSU CHEMICAL CO., LTD. 2004-10-07 US disclosed
US-6787522-B2 BACTERIAL POLYPEPTIDE DEFORMYLASE (PDF) INHIBITORS, N-FORMYL HYDROXYLAMINE DERIVATIVES BRITISH BIOTECH PHARMACEUTICALS (GB) 2004-09-07 US disclosed
EP-1052984-B1 ANTIBACTERIAL AGENTS VERNALIS OXFORD LTD (GB) 2004-05-12 EP disclosed
US-20020165167-A1 Antibacterial agents BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) 2002-11-07 US disclosed
US-6423690-B1 Antibacterial agents BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) 2002-07-23 US disclosed
EP-1052984-A1 ANTIBACTERIAL AGENTS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 2000-11-22 EP disclosed
WO-1999039704-A1 ANTIBACTERIAL AGENTS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1999-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050014702-A1 Antibacterial agents CBR3, CBR1, SIGMAR1 CHRNB2 2616/4885CHRNB4 2096/4885CHRNA4 1935/4885
US-20020165167-A1 Antibacterial agents CBR1, CBR3, SIGMAR1 CHRNB2 2951/4885CHRNB4 2885/4885CHRNA4 2761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.