Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3634366 | 0.83 | CYP1A2 (0.51) | CYP1A2CYP2D6CYP3A4ALDH1A1NFKB1 | |
| SCHEMBL474196 | 0.83 | KMT2A (0.56) | CYP1A2CYP2D6CYP3A4ALDH1A1NFKB1 | |
| SCHEMBL20249044 | 0.81 | CYP1A2 (0.49) | CYP1A2CYP2D6CYP3A4ALDH1A1NFKB1 | |
| SCHEMBL11028511 | 0.81 | CYP1A2 (0.49) | CYP1A2CYP2D6CYP3A4ALDH1A1NFKB1 | |
| SCHEMBL4577893 | 0.81 | CYP1A2 (0.49) | CYP1A2CYP2D6CYP3A4ALDH1A1NFKB1 | |
| SCHEMBL4577891 | 0.81 | CYP1A2 (0.49) | CYP1A2CYP2D6CYP3A4ALDH1A1NFKB1 | |
| SCHEMBL474091 | 0.80 | ALDH1A1 (0.53) | CYP1A2CYP2D6CYP3A4ALDH1A1NFKB1 | |
| SCHEMBL15468358 | 0.79 | CASP2 (0.53) | CYP1A2CYP2D6CYP3A4ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL5041929 | 0.79 | CYP3A4 (0.50) | CYP1A2CYP2D6CYP3A4ALDH1A1NFKB1 | |
| SCHEMBL7345247 | 0.78 | DNM1 (0.53) | CYP1A2CYP2D6ALDH1A1MAPK1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260123-A | Acetaminosulface potassium composition and preparation method thereof | 南通醋酸化工股份有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-115260124-A | Acesulfame potassium composition and method for producing the same | 南通醋酸化工股份有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-114409613-A | Anti-caking acesulfame potassium and preparation method thereof | 南通醋酸化工股份有限公司 | 2022-04-29 | — | — | CN | claimed |
| CN-113896692-A | Preparation method of acesulfame potassium composition | 南通醋酸化工股份有限公司 | 2022-01-07 | — | — | CN | claimed |
| CN-113880787-A | Method for preparing acesulfame potassium | 南通醋酸化工股份有限公司 | 2022-01-04 | — | — | CN | claimed |
| CN-113861083-A | Preparation method of acetoacetyl sulfanilamide triethylamine salt | 南通醋酸化工股份有限公司 | 2021-12-31 | — | — | CN | claimed |
| CN-113788802-A | Method for preparing acesulfame potassium | 南通醋酸化工股份有限公司 | 2021-12-14 | — | — | CN | claimed |
| CN-113773278-A | Acetaminosulface potassium composition and preparation process thereof | 南通醋酸化工股份有限公司 | 2021-12-10 | — | — | CN | claimed |
| CN-113563284-A | Preparation method of acesulfame potassium composition | 南通醋酸化工股份有限公司 | 2021-10-29 | — | — | CN | claimed |
| CN-113563283-A | Preparation method of acesulfame potassium composition | 南通醋酸化工股份有限公司 | 2021-10-29 | — | — | CN | claimed |
| CN-115260124-A | Acesulfame potassium composition and method for producing the same | 南通醋酸化工股份有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-115260123-A | Acetaminosulface potassium composition and preparation method thereof | 南通醋酸化工股份有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-114409613-A | Anti-caking acesulfame potassium and preparation method thereof | 南通醋酸化工股份有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-113896692-A | Preparation method of acesulfame potassium composition | 南通醋酸化工股份有限公司 | 2022-01-07 | — | — | CN | disclosed |
| CN-113880787-A | Method for preparing acesulfame potassium | 南通醋酸化工股份有限公司 | 2022-01-04 | — | — | CN | disclosed |
| WO-2010136458-A1 | PROCESS FOR THE PREPARATION OF N-[2-DIETHYLAMINO)ETHYL]-5-[(5-FLUORO-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)METHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE | RATIOPHARM GMBH (DE) | 2010-12-02 | — | — | WO | disclosed |
| WO-2010136458-A1 | PROCESS FOR THE PREPARATION OF N-[2-DIETHYLAMINO)ETHYL]-5-[(5-FLUORO-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)METHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE | RATIOPHARM GMBH (DE) | 2010-12-02 | — | — | WO | disclosed |
| WO-2009157011-A1 | PROCESS FOR THE PREPARATION OF HIGH PURITY SUNITINIB AND ITS PHARMACEUTICALLY ACCEPTABLE SALT | NATCO PHARMA LIMITED (IN) | 2009-12-30 | — | — | WO | disclosed |
| US-20090062368-A1 | DEUTERIUM-ENRICHED SUNITINIB | PROTIA, LLC (US) | 2009-03-05 | — | — | US | disclosed |
| US-20060009510-A1 | Method of synthesizing indolinone compounds | PHARMACIA & UPJOHN COMPANY LLC | 2006-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062368-A1 | DEUTERIUM-ENRICHED SUNITINIB | SRMS, KDR, ABL1 | CYP1A2 3797/4885CYP2D6 1041/4885CYP3A4 2555/4885 |
| US-20060009510-A1 | Method of synthesizing indolinone compounds | HCCS, ALDH18A1, MKI67 | CYP1A2 288/4885CYP2D6 260/4885CYP3A4 703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.