Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAB1 | Q9Y478 | 16/20 | 1.00 |
| ▸ | PRKAG1 | P54619 | 15/20 | 1.00 |
| ▸ | PRKAA2 | P54646 | 11/20 | 1.00 |
| ▸ | PRKAA1 | Q13131 | 9/20 | 1.00 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.73 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.73 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.73 |
| ▸ | TFDP2 | Q14188 | 1/20 | 0.73 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25735804 | 0.93 | PRKAB1 (0.87) | PRKAB1PRKAG1PRKAA2PRKAA1PRKAG2 | |
| SCHEMBL3481213 | 0.93 | PRKAB1 (0.87) | PRKAB1PRKAG1PRKAA2PRKAA1PRKAG2 | |
| SCHEMBL3481008 | 0.93 | PRKAB1 (0.87) | PRKAB1PRKAG1PRKAA2PRKAA1PRKAG2 | |
| SCHEMBL3481067 | 0.92 | PRKAB1 (0.84) | PRKAB1PRKAG1PRKAA2PRKAA1PRKAG2 | |
| SCHEMBL3481375 | 0.91 | PRKAB1 (0.83) | PRKAB1PRKAG1PRKAA2PRKAA1PRKAG2 | |
| SCHEMBL19876174 | 0.91 | PRKAB1 (0.83) | PRKAB1PRKAG1PRKAA2PRKAA1PRKAG2 | |
| SCHEMBL29659602 | 0.91 | PRKAB1 (0.83) | PRKAB1PRKAG1PRKAA2PRKAA1PRKAG2 | |
| SCHEMBL3481219 | 0.91 | PRKAB1 (0.83) | PRKAB1PRKAG1PRKAA2PRKAA1PRKAG2 | |
| SCHEMBL3481121 | 0.90 | PRKAG1 (0.82) | PRKAB1PRKAG1PRKAA2PRKAA1PRKAG2 | |
| SCHEMBL3481074 | 0.90 | PRKAB1 (0.82) | PRKAB1PRKAG1PRKAA2PRKAA1PRKAG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4599048-A1 | COMPOSITIONS AND METHODS FOR SMALL MOLECULE BASED EXPANSION OF PLURIPOTENT STEM CELLS | Trailhead Biosystems Inc. (US) | 2025-08-13 | — | — | EP | claimed |
| EP-4569090-A2 | METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS | Trailhead Biosystems Inc. (US) | 2025-06-18 | — | — | EP | claimed |
| CN-119654404-A | Methods and compositions for producing oligodendrocyte progenitor cells | 特雷尔赫德生物系统股份有限公司 | 2025-03-18 | — | — | CN | claimed |
| EP-4444870-A1 | METHODS AND COMPOSITIONS FOR GENERATING HUMAN ERYTHROID PROGENITOR CELLS | Trailhead Biosystems Inc. (US) | 2024-10-16 | — | — | EP | claimed |
| CN-118382694-A | Methods and compositions for generating human erythroid progenitors | 特雷尔赫德生物系统股份有限公司 | 2024-07-23 | — | — | CN | claimed |
| WO-2024063818-A9 | METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS | TRAILHEAD BIOSYSTEMS INC. (US) | 2024-05-23 | — | — | WO | claimed |
| WO-2024076758-A1 | COMPOSITIONS AND METHODS FOR SMALL MOLECULE BASED EXPANSION OF PLURIPOTENT STEM CELLS | TRAILHEAD BIOSYSTEMS INC. (US) | 2024-04-11 | — | — | WO | claimed |
| US-20240117302-A1 | COMPOSITIONS AND METHODS FOR SMALL MOLECULE BASED EXPANSION OF PLURIPOTENT STEM CELLS | TRAILHEAD BIOSYSTEMS INC. | 2024-04-11 | — | — | US | claimed |
| WO-2024063818-A2 | METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS | TRAILHEAD BIOSYSTEMS INC. (US) | 2024-03-28 | — | — | WO | claimed |
| US-20240043798-A1 | METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS | TRAILHEAD BIOSYSTEMS INC. | 2024-02-08 | — | — | US | claimed |
| US-20240034761-A1 | REGENERATION OF MAMMALIAN TISSUES USING SYNTHETIC IMMODULINS | MASCARENHAS DESMOND (US) | 2024-02-01 | — | — | US | claimed |
| WO-2023107477-A1 | METHODS AND COMPOSITIONS FOR GENERATING HUMAN ERYTHROID PROGENITOR CELLS | TRAILHEAD BIOSYSTEMS INC. (US) | 2023-06-15 | — | — | WO | claimed |
| US-20230174938-A1 | METHODS AND COMPOSITIONS FOR GENERATING HUMAN ERYTHROID PROGENITOR CELLS | TRAILHEAD BIOSYSTEMS INC. | 2023-06-08 | — | — | US | claimed |
| CN-115975911-A | Use of AMPK activators to increase the efficiency of differentiation of mammalian pluripotent stem cells into definitive endoderm cells | 武汉大学 | 2023-04-18 | — | — | CN | claimed |
| WO-2022192042-A2 | REGENERATION OF MAMMALIAN TISSUES USING SYNTHETIC IMMODULINS | MASCARENHAS DESMOND (US) | 2022-09-15 | — | — | WO | claimed |
| EP-3723754-B1 | IMIDAZO [1,2-C] QUINAZOLIN-5-AMINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES | MERCK SHARP & DOHME LLC (US) | 2026-05-13 | — | — | EP | disclosed |
| US-12610731-B2 | Organic light emitting diode and organic light emitting device including the same | LG DISPLAY CO., LTD. (KR) | 2026-04-21 | — | — | US | disclosed |
| US-20100081643-A1 | NOVEL CYCLIC BENZIMIDAZOLE DERIVATIVES USEFUL AS ANTI-DIABETIC AGENTS | MERCK SHARP & DOHME LLC | 2010-04-01 | — | — | US | disclosed |
| US-20100081643-A1 | NOVEL CYCLIC BENZIMIDAZOLE DERIVATIVES USEFUL AS ANTI-DIABETIC AGENTS | MERCK SHARP & DOHME LLC | 2010-04-01 | — | — | US | disclosed |
| WO-2010025553-A1 | HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2010-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081643-A1 | NOVEL CYCLIC BENZIMIDAZOLE DERIVATIVES USEFUL AS ANTI-DIABETIC AGENTS | PRKAG2, PRKAG1, PRKAB2 | PRKAB1 5/4885PRKAG1 2/4885PRKAA2 12/4885 |
| US-12610731-B2 | Organic light emitting diode and organic light emitting device including the same | SOD1, ROS1, OXA1L | PRKAB1 3901/4885PRKAG1 4206/4885PRKAA2 4397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.