Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F3 | P13726 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.61 |
| ▸ | MAOA | P21397 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | P4HB | P07237 | 1/20 | 0.57 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.57 |
| ▸ | XDH | P47989 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3483600 | 1.00 | F3 (0.66) | F3MAPTRAB9AMAOBMAOA | |
| SCHEMBL25199608 | 0.89 | XDH (0.57) | F3MAPTRAB9AMAOBESR1 | |
| SCHEMBL25232308 | 0.89 | XDH (0.57) | F3MAPTRAB9AMAOBESR1 | |
| SCHEMBL25422136 | 0.89 | XDH (0.57) | F3MAPTRAB9AMAOBESR1 | |
| SCHEMBL3483672 | 0.85 | MAPT (0.62) | MAPTPOLBCXCL12KMT2AMEN1 | |
| SCHEMBL3483669 | 0.85 | MAPT (0.62) | MAPTPOLBCXCL12KMT2AMEN1 | |
| SCHEMBL3483881 | 0.84 | F3 (0.64) | F3MAPTESR1ESR2CXCL12 | |
| SCHEMBL3483883 | 0.84 | F3 (0.64) | F3MAPTESR1ESR2CXCL12 | |
| SCHEMBL25198564 | 0.84 | P4HB (0.67) | MAPTRAB9AMAOBP4HBLMNA | |
| SCHEMBL25201162 | 0.84 | P4HB (0.67) | MAPTRAB9AMAOBP4HBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601943-B1 | Anti-cancer composition containing chalcone compounds | SEOUL NAT UNIV IND FOUNDATION (KR) | 2015-07-22 | — | — | EP | claimed |
| US-20130178533-A1 | COMPOSITION FOR DIAGNOSING, TREATING, AND PREVENTING LIVER DISEASE | SNU R&DB FOUNDATION (KR) | 2013-07-11 | — | — | US | claimed |
| EP-2601943-A1 | Anti-cancer composition containing chalcone compounds | Seoul National University Industry Foundation (KR) | 2013-06-12 | — | — | EP | claimed |
| US-7851654-B2 | Chalcone derivatives, pharmaceutically acceptable salt, method for preparation and uses thereof | INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY (KR) | 2010-12-14 | — | — | US | claimed |
| US-20100068730-A1 | METHOD FOR SCREENING ANTI-CANCER COMPOUNDS INHIBITING FUNCTION OF TM4SF5 AND ANTI-CANCER COMPOSITION CONTAINING CHALCONE COMPOUNDS | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2010-03-18 | — | — | US | claimed |
| US-20090252694-A1 | Novel Chalcone Derivatives, Pharmaceutically Acceptable Salt, Method for Preparation and Uses Thereof | INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSTIY (KR) | 2009-10-08 | — | — | US | claimed |
| EP-2099440-A1 | METHOD FOR SCREENING ANTI-CANCER COMPOUNDS INHIBITING FUNCTION OF TM4SF5 AND ANTI-CANCER COMPOSITION CONTAINING CHALCONE COMPOUNDS | Seoul National University Industry Foundation (KR) | 2009-09-16 | — | — | EP | claimed |
| WO-2008069608-A1 | METHOD FOR SCREENING ANTI-CANCER COMPOUNDS INHIBITING FUNCTION OF TM4SF5 AND ANTI-CANCER COMPOSITION CONTAINING CHALCONE COMPOUNDS | SEOUL NATIONALUNIVERSITY INDUSTRY FOUNDATION (KR) | 2008-06-12 | — | — | WO | claimed |
| WO-2007114532-A1 | NOVEL CHALCONE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT, METHOD FOR PREPARATION AND USES THEREOF | INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY (KR) | 2007-10-11 | — | — | WO | claimed |
| US-20260014100-A1 | Compositions and Methods for Treating Bleeding and Bleeding Disorders | YEWSAVIN INC (US) | 2026-01-15 | — | — | US | disclosed |
| US-12343317-B2 | Compositions and methods for treating bleeding and bleeding disorders | YewSavin, Inc. (US) | 2025-07-01 | — | — | US | disclosed |
| WO-2024233598-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2024-11-14 | — | — | WO | disclosed |
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| US-20230190679-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-06-22 | — | — | US | disclosed |
| US-7851654-B2 | Chalcone derivatives, pharmaceutically acceptable salt, method for preparation and uses thereof | INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY (KR) | 2010-12-14 | — | — | US | disclosed |
| US-20100068730-A1 | METHOD FOR SCREENING ANTI-CANCER COMPOUNDS INHIBITING FUNCTION OF TM4SF5 AND ANTI-CANCER COMPOSITION CONTAINING CHALCONE COMPOUNDS | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2010-03-18 | — | — | US | disclosed |
| US-20090252694-A1 | Novel Chalcone Derivatives, Pharmaceutically Acceptable Salt, Method for Preparation and Uses Thereof | INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSTIY (KR) | 2009-10-08 | — | — | US | disclosed |
| EP-2099440-A1 | METHOD FOR SCREENING ANTI-CANCER COMPOUNDS INHIBITING FUNCTION OF TM4SF5 AND ANTI-CANCER COMPOSITION CONTAINING CHALCONE COMPOUNDS | Seoul National University Industry Foundation (KR) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008069608-A1 | METHOD FOR SCREENING ANTI-CANCER COMPOUNDS INHIBITING FUNCTION OF TM4SF5 AND ANTI-CANCER COMPOSITION CONTAINING CHALCONE COMPOUNDS | SEOUL NATIONALUNIVERSITY INDUSTRY FOUNDATION (KR) | 2008-06-12 | — | — | WO | disclosed |
| WO-2007114532-A1 | NOVEL CHALCONE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALT, METHOD FOR PREPARATION AND USES THEREOF | INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITY (KR) | 2007-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090252694-A1 | Novel Chalcone Derivatives, Pharmaceutically Acceptable Salt, Method for Preparation and Uses Thereof | TYR, CYP21A2, CMA1 | F3 1341/4885MAPT 4199/4885RAB9A 2802/4885 |
| US-20260014100-A1 | Compositions and Methods for Treating Bleeding and Bleeding Disorders | SERPINC1, F2, F13B | F3 5/4885MAPT 3297/4885RAB9A 480/4885 |
| US-20230190679-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | SERPINC1, SERPINE1, SERPINH1 | F3 11/4885MAPT 3512/4885RAB9A 1327/4885 |
| US-12343317-B2 | Compositions and methods for treating bleeding and bleeding disorders | SERPINC1, SERPINE1, SERPINH1 | F3 11/4885MAPT 3512/4885RAB9A 1327/4885 |
| US-20100068730-A1 | METHOD FOR SCREENING ANTI-CANCER COMPOUNDS INHIBITING FUNCTION OF TM4SF5 AND ANTI-CANCER COMPOSITION CONTAINING CHALCONE COMPOUNDS | TM9SF4, TM9SF2, TM9SF3 | F3 170/4885MAPT 4397/4885RAB9A 3467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.