SCHEMBL945221

SCHEMBL945221

O=S(=O)(CCc1ccccc1SSc1ccccc1CCS(=O)(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSIP1 O75475 1/20 0.44
APOBEC3G Q9HC16 1/20 0.42
HSD11B1 P28845 5/20 0.42
L3MBTL1 Q9Y468 1/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
MMP3 P08254 1/20 0.38
MMP8 P22894 1/20 0.38
MMP13 P45452 1/20 0.38
HDAC1 Q13547 2/20 0.38
HDAC8 Q9BY41 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.37
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC10 Q969S8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3483640 0.81 PSIP1 (0.47) PSIP1APOBEC3GHSD11B1L3MBTL1KMT2A
SCHEMBL777601 0.73 PSIP1 (0.67) PSIP1HSD11B1L3MBTL1KMT2AMEN1
SCHEMBL3241520 0.72 LOX (0.54) PSIP1HSD11B1L3MBTL1KMT2AMMP13
SCHEMBL945222 0.71 HDAC1 (0.48) PSIP1HSD11B1L3MBTL1KMT2AKEAP1
SCHEMBL6748136 0.70 HSD11B1 (0.40) PSIP1HSD11B1L3MBTL1KMT2AMEN1
SCHEMBL14936576 0.70 POLB (0.51) HSD11B1L3MBTL1KMT2AMEN1HDAC1
SCHEMBL576918 0.69 KEAP1 (0.63) PSIP1HSD11B1L3MBTL1KMT2AMEN1
SCHEMBL10629823 0.69 PSIP1 (0.61) PSIP1HSD11B1L3MBTL1KMT2AMEN1
SCHEMBL2870934 0.69 PSIP1 (0.54) PSIP1HSD11B1L3MBTL1KMT2AMEN1
SCHEMBL945033 0.69 APOBEC3G (0.52) APOBEC3GALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987516-B2 Process for producing arylsulfur pentafluorides UBE INDUSTRIES, LTD. (JP) 2015-03-24 US disclosed
US-20110004022-A1 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2011-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110004022-A1 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA PSIP1 313/4885APOBEC3G 1330/4885HSD11B1 1564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.