Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 5/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3484675 | 0.89 | RIPK1 (0.41) | SLC1A5RIPK1PPARAPPARGSLC6A2 | |
| SCHEMBL4040101 | 0.86 | PPARA (0.48) | SLC1A5RIPK1PPARAPPARDPPARG | |
| SCHEMBL3484402 | 0.81 | PPARG (0.44) | PPARAPPARDPPARGPOLBMTNR1B | |
| SCHEMBL3484748 | 0.78 | PTGDR2 (0.37) | PPARAPPARGSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6955048 | 0.75 | SLC6A2 (0.50) | RIPK1SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL3483934 | 0.75 | HTT (0.43) | PPARAPPARDPPARGPOLBMTNR1B | |
| SCHEMBL4041637 | 0.75 | PPARG (0.54) | RIPK1PPARAPPARDPPARGSLC6A2 | |
| SCHEMBL4576129 | 0.74 | CYP1A2 (0.41) | PPARAPPARGKDM4EFBP1MEN1 | |
| SCHEMBL30609812 | 0.74 | CYP1A2 (0.41) | PPARAPPARGKDM4EFBP1MEN1 | |
| SCHEMBL3484417 | 0.73 | PPARA (0.40) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100004159-A1 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATIONS AND USES | GENFIT (FR) | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004159-A1 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATIONS AND USES | IPO5, PPIP5K2, IPO4 | SLC1A5 948/4885RIPK1 2544/4885PPARA 1045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.