SCHEMBL348535

SCHEMBL348535

O=C1C=CC(=O)N1c1ccc(Oc2ccc(Cc3ccc(Oc4ccc(N5C(=O)C=CC5=O)cc4)c(Br)c3)cc2Br)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 14/20 0.54
FAAH O00519 5/20 0.54
HSP90AA1 P07900 3/20 0.41
PKM P14618 2/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
HPGD P15428 1/20 0.41
HTT P42858 1/20 0.41
CCR6 P51684 1/20 0.41
KMT2A Q03164 1/20 0.41
ATM Q13315 1/20 0.41
NTRK1 P04629 1/20 0.40
NTRK3 Q16288 1/20 0.40
NTRK2 Q16620 1/20 0.40
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
MAPK1 P28482 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8852750 0.89 MGLL (0.56) MGLLFAAHHSP90AA1PKMMEN1
SCHEMBL8852819 0.87 MGLL (0.58) MGLLFAAHHSP90AA1PKMMEN1
SCHEMBL348925 0.83 MGLL (0.54) MGLLFAAHHSP90AA1PKMMEN1
SCHEMBL349582 0.83 MGLL (0.54) MGLLFAAHHSP90AA1PKMMEN1
SCHEMBL15442737 0.82 MGLL (0.54) MGLLFAAHHSP90AA1PKMMEN1
SCHEMBL349106 0.80 MGLL (0.78) MGLLFAAHHSP90AA1PKMMEN1
SCHEMBL348949 0.78 MGLL (0.49) MGLLFAAHHSP90AA1PKMMEN1
SCHEMBL348030 0.78 MGLL (0.47) MGLLFAAHHSP90AA1PKMMEN1
SCHEMBL30394652 0.78 MGLL (0.49) MGLLFAAHHSP90AA1PKMMEN1
SCHEMBL7605828 0.74 MAPT (0.46) MEN1ALDH1A1KMT2AMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0449292-B1 Multilayer printed circuit board and production thereof HITACHI LTD (JP) 1997-08-20 EP claimed
US-20190203048-A1 Maleimide Resin Composition, Prepreg, Cured Product Of Same And Semiconductor Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2019-07-04 US disclosed
CN-109563344-A Maleimide resin composition, prepreg, its hardening thing and semiconductor device 日本化药株式会社 2019-04-02 CN disclosed
EP-1646486-B1 Process for preparing medical devices BOSTON SCIENT LTD (BB) 2012-02-22 EP disclosed
US-20120013043-A1 MEDICAL DEVICES AND PROCESSES FOR PREPARING SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-01-19 US disclosed
US-8025637-B2 Medical balloons and processes for preparing same BOSTON SCIENTIFIC SCIMED, INC. (US) 2011-09-27 US disclosed
US-7649027-B2 having juts via photopolymerization in supercritical carbon dioxide; calcining KANSAI PAINT CO., LTD. (JP) 2010-01-19 US disclosed
US-20090023830-A1 POLYMER AND PROCESS FOR PRODUCING POLYMER KANSAI PAINT CO., LTD. (JP) 2009-01-22 US disclosed
EP-1698647-A1 POLYMER AND PROCESS FOR PRODUCING POLYMER KANSAI PAINT CO., LTD. (JP) 2006-09-06 EP disclosed
US-7081486-B2 Method of producing polymer SHIZUOKA UNIVERSITY (JP) 2006-07-25 US disclosed
US-6132852-A LAMINATE OF POLYMER CONDUCTOR AND DIELECTRIC HITACHI, LTD. (JP) 2000-10-17 US disclosed
EP-0618269-B1 Thermosetting resin compositions and their use for making resin articles and thin film wiring boards HITACHI LTD (JP) 1998-11-11 EP disclosed
EP-0449292-B1 Multilayer printed circuit board and production thereof HITACHI LTD (JP) 1997-08-20 EP disclosed
EP-0755979-A2 Thermosetting resin compositions and their use for thin film wiring boards HITACHI, LTD. (JP) 1997-01-29 EP disclosed
EP-0476589-B1 Multi-layer wiring substrate and production thereof HITACHI LTD (JP) 1996-06-12 EP disclosed
EP-0618269-A1 Thermosetting resin compositions and their use for thin film wiring boards HITACHI, LTD. (JP) 1994-10-05 EP disclosed
US-5352762-A Fluorine-containing biscyanamide thermosetting resin, heat resistance, adhesion HITACHI, LTD. (JP) 1994-10-04 US disclosed
US-5225499-A Molding materials of epoxy resins and ether imides HITACHI, LTD. (JP) 1993-07-06 US disclosed
EP-0476589-A2 Multi-layer wiring substrate and production thereof HITACHI, LTD. (JP) 1992-03-25 EP disclosed
EP-0449292-A2 Multilayer printed circuit board and production thereof HITACHI, LTD. (JP) 1991-10-02 EP disclosed