Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.54 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 4/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 4/20 | 0.41 |
| ▸ | CPA1 | P15085 | 3/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3049728 | 0.81 | RAB9A (0.50) | ITGB1ITGA4ADAMTS4ALDH1A1 | |
| SCHEMBL29882565 | 0.81 | RAB9A (0.50) | ITGB1ITGA4ADAMTS4ALDH1A1 | |
| SCHEMBL1285863 | 0.81 | RAB9A (0.50) | ITGB1ITGA4ADAMTS4ALDH1A1 | |
| SCHEMBL29200872 | 0.77 | FPR2 (0.61) | ITGB1ITGA4ACEMMECPA1 | |
| SCHEMBL10077502 | 0.77 | FPR2 (0.61) | ITGB1ITGA4ACEMMECPA1 | |
| SCHEMBL10077503 | 0.77 | FPR2 (0.61) | ITGB1ITGA4ACEMMECPA1 | |
| SCHEMBL504108 | 0.75 | ALDH1A1 (0.61) | ACEALDH1A1MMECPA1ACE2 | |
| SCHEMBL27547070 | 0.75 | ALDH1A1 (0.61) | ACEALDH1A1MMECPA1ACE2 | |
| SCHEMBL5996017 | 0.75 | ALDH1A1 (0.61) | ACEALDH1A1MMECPA1ACE2 | |
| Valine SCHEMBL7689739 | 0.71 | ALDH1A1 (0.51) | MAPK1ACEALDH1A1MMECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118241-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) | 2010-10-14 | — | — | WO | disclosed |