Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ACE | P12821 | 3/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | MME | P08473 | 3/20 | 0.53 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.52 |
| ▸ | CPA1 | P15085 | 2/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GNPAT | O15228 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | PAM | P19021 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5996017 | 1.00 | ALDH1A1 (0.61) | ALDH1A1LMNAACEITGB3ITGA2B | |
| SCHEMBL27547070 | 1.00 | ALDH1A1 (0.61) | ALDH1A1LMNAACEITGB3ITGA2B | |
| Valine SCHEMBL7689739 | 0.89 | ALDH1A1 (0.51) | ALDH1A1LMNAACEITGB3ITGA2B | |
| SCHEMBL5995731 | 0.89 | MME (0.63) | ALDH1A1LMNAACEMMECPA1 | |
| SCHEMBL31688037 | 0.87 | MME (0.52) | ALDH1A1LMNAACEITGB3ITGA2B | |
| Acetyl Tyrosine SCHEMBL8977600 | 0.85 | FOLH1 (0.66) | LMNAACEITGB3ITGA2BCA2 | |
| SCHEMBL5061764 | 0.85 | LMNA (0.61) | LMNAACEITGB3ITGA2BMME | |
| Acetyl Tyrosine SCHEMBL8977601 | 0.85 | FOLH1 (0.66) | LMNAACEITGB3ITGA2BCA2 | |
| SCHEMBL14031836 | 0.85 | LMNA (0.61) | LMNAACEITGB3ITGA2BMME | |
| SCHEMBL11122115 | 0.85 | LMNA (0.61) | LMNAACEITGB3ITGA2BMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | claimed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | claimed |
| US-11274126-B2 | pH-sensitive cyclic peptides | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) | 2022-03-15 | — | — | US | claimed |
| EP-3432908-A1 | pH-SENSITIVE PEPTIDES | Rhode Island Council on Postsecondary Education (US) | 2019-01-30 | — | — | EP | claimed |
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2018-09-11 | — | — | US | claimed |
| WO-2017165452-A1 | pH-SENSITIVE PEPTIDES | RHODE ISLAND COUNCIL ON POSTSECONDARY EDUCATION (US) | 2017-09-28 | — | — | WO | claimed |
| US-20160176922-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | Indiana University Research and Technology Corpora tion (US) | 2016-06-23 | — | — | US | claimed |
| US-9217012-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-12-22 | — | — | US | claimed |
| US-20120088720-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) | 2012-04-12 | — | — | US | claimed |
| WO-2010118241-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) | 2010-10-14 | — | — | WO | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| WO-2002068586-A2 | HIV/FIV PROTEASE INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2002-09-06 | — | — | WO | claimed |
| EP-3303367-B1 | STABILIZED MINIMAL COILED-COIL MIMETICS | UNIV NEW YORK (US) | 2025-06-18 | — | — | EP | disclosed |
| US-12290575-B2 | Fluorescent compound comprising a fluorophore conjugated to a pH-triggered polypeptide | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) | 2025-05-06 | — | — | US | disclosed |
| US-20240148911-A1 | FLUORESCENT COMPOUND COMPRISING A FLUOROPHORE CONJUGATED TO A pH-TRIGGERED POLYPEPTIDE | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES | 2024-05-09 | — | — | US | disclosed |
| US-20240124539-A1 | CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME | NEW YORK UNIVERSITY | 2024-04-18 | — | — | US | disclosed |
| US-20020127577-A1 | Bioactive sensors | GRAFFINITY PHARMACEUTICALS AG (DE) | 2002-09-12 | — | — | US | disclosed |
| WO-2002068586-A2 | HIV/FIV PROTEASE INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2002-09-06 | — | — | WO | disclosed |
| EP-1185869-A2 | LIGAND-ANCHOR CONJUGATES FOR PRODUCING A BIOSENSOR LAYER | Graffinity Pharmaceutical Design GmbH (DE) | 2002-03-13 | — | — | EP | disclosed |
| WO-2000073796-A2 | LIGAND-ANCHOR CONJUGATES FOR PRODUCING A BIOSENSOR LAYER | GRAFFINITY PHARMACEUTICAL DESIGN GMBH (DE) | 2000-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11274126-B2 | pH-sensitive cyclic peptides | VIP, PHLPP1, PHLPP2 | ALDH1A1 4877/4885LMNA 1886/4885ACE 3009/4885 |
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | PTPRCAP, PTPRF, PTPRS | ALDH1A1 3087/4885LMNA 4734/4885ACE 1522/4885 |
| US-20160176922-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | PTPRCAP, PTPRF, PTPRS | ALDH1A1 3087/4885LMNA 4734/4885ACE 1522/4885 |
| US-20240148911-A1 | FLUORESCENT COMPOUND COMPRISING A FLUOROPHORE CONJUGATED TO A pH-TRIGGERED POLYPEPTIDE | NPPA, LNPEP, VIP | ALDH1A1 2449/4885LMNA 755/4885ACE 764/4885 |
| US-20240124539-A1 | CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME | SOS2, SOS1, F2 | ALDH1A1 3199/4885LMNA 1476/4885ACE 4710/4885 |
| US-12290575-B2 | Fluorescent compound comprising a fluorophore conjugated to a pH-triggered polypeptide | NPPA, LNPEP, VIP | ALDH1A1 2449/4885LMNA 755/4885ACE 764/4885 |
| US-20120088720-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | PTPRCAP, PTPRF, PTPRS | ALDH1A1 3087/4885LMNA 4734/4885ACE 1522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.