Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25306980 | 0.86 | MAPT (0.54) | MAPTRXFP1ALDH1A1MEN1KMT2A | |
| SCHEMBL11833858 | 0.84 | RXFP1 (0.54) | MAPTRXFP1ALDH1A1P2RX1LMNA | |
| SCHEMBL8569299 | 0.82 | MAPT (0.67) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13440495 | 0.81 | TP53 (0.60) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL11243814 | 0.81 | ALDH1A1 (0.51) | MAPTRXFP1ALDH1A1MEN1KMT2A | |
| SCHEMBL24095596 | 0.80 | SMN1; SMN2 (0.55) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8569129 | 0.80 | ALDH1A1 (0.62) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL24095743 | 0.79 | RXFP1 (0.58) | MAPTRXFP1MEN1KMT2AP2RX1 | |
| SCHEMBL11639893 | 0.77 | LIPC (0.49) | MAPTRXFP1ALDH1A1MEN1KMT2A | |
| SCHEMBL8568341 | 0.77 | AKR1C4 (0.52) | MAPTALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2100507-B1 | QUINAZOLINE DERIVATIVES CAPABLE OF INHIBITING CYTOKININ SIGNALING | SUMITOMO CHEMICAL CO (JP) | 2015-02-25 | — | — | EP | disclosed |
| US-8722580-B2 | Agent for inhibiting cytokinin signaling | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-05-13 | — | — | US | disclosed |
| US-20100056377-A1 | AGENT FOR INHIBITING CYTOKININ SIGNALING | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-04 | — | — | US | disclosed |
| EP-2100507-A1 | SUBSTANCE CAPABLE OF INHIBITING CYTOKININ SIGNALING | Sumitomo Chemical Company, Limited (JP) | 2009-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056377-A1 | AGENT FOR INHIBITING CYTOKININ SIGNALING | CROCC, STAT3, GRK6 | MAPT 4826/4885RXFP1 196/4885ALDH1A1 2316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.