Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | PKM | P14618 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4009985 | 0.88 | POLB (0.80) | ALDH1A1MAPTRAB9APOLBTSHR | |
| SCHEMBL4004216 | 0.79 | DRD4 (0.63) | PKMMAPTRAB9APOLBDRD2 | |
| SCHEMBL29078376 | 0.75 | KMT2A (0.69) | ALDH1A1MAPTMAPK1POLBTSHR | |
| SCHEMBL4009678 | 0.75 | RAB9A (0.52) | ALDH1A1PKMMAPTRAB9APOLB | |
| SCHEMBL2984890 | 0.75 | CYP1A2 (0.59) | ALDH1A1MAPTMAPK1POLBTSHR | |
| SCHEMBL6350328 | 0.74 | KDM4E (1.00) | ALDH1A1TSHRKDM4EHTTSMN1; SMN2 | |
| SCHEMBL4006615 | 0.73 | DRD4 (1.00) | ALDH1A1KDM4EDRD2DRD4DRD3 | |
| SCHEMBL4002897 | 0.73 | RAB9A (0.49) | ALDH1A1PKMMAPTRAB9APOLB | |
| SCHEMBL8358036 | 0.71 | POLB (0.72) | ALDH1A1MAPTMAPK1POLBTSHR | |
| SCHEMBL8017080 | 0.71 | ALDH1A1 (0.64) | ALDH1A1MAPTRAB9AMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012419-B2 | Methods and compositions related to eosinophil regulation | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2015-04-21 | — | — | US | disclosed |
| US-9012419-B2 | Methods and compositions related to eosinophil regulation | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2015-04-21 | — | — | US | disclosed |
| US-9012419-B2 | Methods and compositions related to eosinophil regulation | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2015-04-21 | — | — | US | disclosed |
| US-20100016410-A1 | Methods and Compositions Related to Eosinophil Regulation | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-01-21 | — | — | US | disclosed |
| US-20100016410-A1 | Methods and Compositions Related to Eosinophil Regulation | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-01-21 | — | — | US | disclosed |
| US-20100016410-A1 | Methods and Compositions Related to Eosinophil Regulation | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-01-21 | — | — | US | disclosed |
| WO-2007136707-A2 | METHODS AND COMPOSITIONS RELATED TO EOSINOPHIL REGULATION | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2007-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016410-A1 | Methods and Compositions Related to Eosinophil Regulation | EPX, CCL11, ELANE | ALDH1A1 2022/4885PKM 4482/4885MAPT 4831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.