Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345401 | 0.79 | — | — | |
| SCHEMBL7354510 | 0.79 | KDM4E (0.50) | ALDH1A1KDM4EGAAKMT2ATDP1 | |
| SCHEMBL7351663 | 0.77 | KDM4E (0.53) | ALDH1A1KDM4EGAAMAPTKMT2A | |
| SCHEMBL22407037 | 0.75 | CTH (0.38) | ALDH1A1KDM4EGAAMAPTKMT2A | |
| SCHEMBL12539457 | 0.71 | KDM4E (0.60) | ALDH1A1KDM4EGAAMAPTHTT | |
| SCHEMBL20583677 | 0.71 | KDM4E (0.38) | ALDH1A1KDM4EGAAKMT2ATDP1 | |
| SCHEMBL18641821 | 0.69 | KDM4E (0.37) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL18989201 | 0.68 | KDM4E (0.34) | ALDH1A1KDM4EGAAMAPTKMT2A | |
| SCHEMBL12539642 | 0.67 | KDM4E (0.47) | ALDH1A1KDM4EGAAMAPTRAB9A | |
| SCHEMBL2305380 | 0.67 | KDM4E (0.35) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100094000-A1 | PYRAZOLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100094000-A1 | PYRAZOLE COMPOUNDS | NR3C2, MC2R, NR3C1 | ALDH1A1 1704/4885KDM4E 3578/4885GAA 4647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.