Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL594792 | 0.84 | NPC1 (0.33) | RAB9AALDH1A1MGLLSMN1; SMN2P2RX7 | |
| SCHEMBL4986617 | 0.84 | NPC1 (0.33) | RAB9AALDH1A1MGLLSMN1; SMN2P2RX7 | |
| SCHEMBL2493301 | 0.84 | NPC1 (0.33) | RAB9AALDH1A1MGLLSMN1; SMN2P2RX7 | |
| SCHEMBL6758348 | 0.78 | P2RX7 (0.34) | CES2CES1RAB9AALDH1A1MGLL | |
| SCHEMBL3390440 | 0.73 | ALDH1A1 (0.34) | RAB9AALDH1A1MGLLP2RX7NPC1 | |
| SCHEMBL8718920 | 0.72 | HPGD (0.33) | CES2CES1RAB9AALDH1A1TDP1 | |
| SCHEMBL2471234 | 0.72 | HPGD (0.33) | CES2CES1RAB9AALDH1A1TDP1 | |
| SCHEMBL8960840 | 0.63 | SLC6A2 (0.33) | RAB9AALDH1A1MGLLP2RX7NPC1 | |
| SCHEMBL6842407 | 0.63 | SLC6A2 (0.33) | RAB9AALDH1A1MGLLP2RX7NPC1 | |
| SCHEMBL8112015 | 0.62 | KMT2A (0.33) | CES2CES1ALDH1A1P2RX7GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100210833-A1 | METHOD OF PRODUCING NUCLEOSIDES | CILAG AG (CH) | 2010-08-19 | — | — | US | disclosed |