Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 4/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6842407 | 0.84 | SLC6A2 (0.33) | P2RX7ALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL3497068 | 0.78 | CES2 (0.34) | P2RX7CES2CES1ALDH1A1RAB9A | |
| SCHEMBL8044926 | 0.75 | P2RX7 (0.32) | P2RX7CES2CES1PTGS2GAA | |
| SCHEMBL4750928 | 0.70 | SLC6A2 (0.31) | P2RX7ALDH1A1 | |
| SCHEMBL4411815 | 0.69 | CTNNB1 (0.32) | P2RX7ALDH1A1MGLL | |
| SCHEMBL1799676 | 0.66 | TDP1 (0.33) | ALDH1A1RAB9ANPC1TDP1 | |
| SCHEMBL3390440 | 0.63 | ALDH1A1 (0.34) | P2RX7ALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL28032552 | 0.63 | CES2 (0.60) | CES2CES1ALDH1A1RAB9APOLB | |
| SCHEMBL4986617 | 0.63 | NPC1 (0.33) | P2RX7ALDH1A1RAB9APOLBNPC1 | |
| SCHEMBL594792 | 0.63 | NPC1 (0.33) | P2RX7ALDH1A1RAB9APOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716971-B1 | CAN BE USED IN THE CHEMICAL SYNTHESIS OF FLUORESCENT OLIGONUCLEOTIDE. | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2004-04-06 | — | — | US | disclosed |