Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | YAP1 | P46937 | 1/20 | 0.54 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.52 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | BCL2 | P10415 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498679 | 1.00 | CTSS (0.56) | CTSSCTSKGRM5YAP1KLK5 | |
| SCHEMBL3498818 | 0.89 | YAP1 (0.54) | YAP1KLK5PTPN1BCL2MAOB | |
| SCHEMBL3500952 | 0.89 | CACNA1B (0.55) | YAP1KLK5PTPN1BCL2MAOB | |
| SCHEMBL3499367 | 0.89 | CTSS (0.57) | CTSSCTSKYAP1KLK5GPR34 | |
| SCHEMBL3499368 | 0.89 | CTSS (0.57) | CTSSCTSKYAP1KLK5GPR34 | |
| SCHEMBL3350988 | 0.87 | BCL2 (0.64) | CTSSCTSKYAP1KLK5PTPN1 | |
| SCHEMBL3500186 | 0.87 | BCL2 (0.64) | CTSSCTSKYAP1KLK5PTPN1 | |
| SCHEMBL6161729 | 0.87 | BCL2 (0.64) | CTSSCTSKYAP1KLK5PTPN1 | |
| SCHEMBL4934696 | 0.85 | PTPN1 (0.58) | CTSSCTSKYAP1KLK5PTPN1 | |
| SCHEMBL4934701 | 0.85 | PTPN1 (0.58) | CTSSCTSKYAP1KLK5PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| EP-1849465-A1 | AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR | Takeda Pharmaceutical Company Limited (JP) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | GPR34, GPR4, GPR6 | CTSS 3589/4885CTSK 3253/4885GRM5 122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.