Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | MMP14 | P50281 | 1/20 | 0.59 |
| ▸ | CDC7 | O00311 | 3/20 | 0.51 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.49 |
| ▸ | F9 | P00740 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9431623 | 0.87 | CYP11B2 (0.62) | MMP2MMP13MMP14CYP11B1CYP11B2 | |
| SCHEMBL3500033 | 0.81 | MAPT (0.56) | MMP2MMP13MMP14F9F10 | |
| SCHEMBL3499177 | 0.81 | MKNK1 (0.55) | CYP11B1CYP11B2CYP19A1F9MKNK1 | |
| SCHEMBL19964502 | 0.80 | CHEK1 (0.57) | CYP11B1CYP11B2CYP19A1F9MKNK1 | |
| SCHEMBL11070341 | 0.80 | CDC7 (0.53) | CDC7DBF4KDM4EMAPTNPC1 | |
| SCHEMBL3498021 | 0.79 | MAPT (0.50) | F9F10KDM4EMAPTALDH1A1 | |
| SCHEMBL3498454 | 0.79 | MAPK14 (0.54) | F9F10KDM4EMAPTNPC1 | |
| SCHEMBL3498640 | 0.78 | MAPT (0.52) | F9F10KDM4EMAPTMEN1 | |
| SCHEMBL5487018 | 0.78 | CYP11B2 (0.74) | MMP2MMP13MMP14CYP11B1CYP11B2 | |
| SCHEMBL842776 | 0.77 | GSK3B (0.60) | CDC7DBF4MAPTALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| EP-1849465-A1 | AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR | Takeda Pharmaceutical Company Limited (JP) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | GPR34, GPR4, GPR6 | MMP2 3984/4885MMP13 3858/4885MMP14 2821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.