SCHEMBL497168

SCHEMBL497168

NC(N)(CCC(=O)O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.54
KMT2A Q03164 3/20 0.54
ALDH1A1 P00352 3/20 0.54
CYP1A2 P05177 2/20 0.54
MEN1 O00255 2/20 0.54
NAALAD2 Q9Y3Q0 1/20 0.46
LMNA P02545 6/20 0.42
ALKBH5 Q6P6C2 1/20 0.42
SUCNR1 Q9BXA5 1/20 0.42
EGLN1 Q9GZT9 1/20 0.42
SLC22A6 Q4U2R8 1/20 0.38
TSHR P16473 3/20 0.38
GABRR1 P24046 2/20 0.38
HDAC3 O15379 2/20 0.38
HDAC1 Q13547 2/20 0.38
HDAC2 Q92769 2/20 0.38
HDAC8 Q9BY41 2/20 0.38
BLM P54132 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
GABRP O00591 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28548595 0.97 THRB (0.52) THRBKMT2AALDH1A1CYP1A2MEN1
SCHEMBL497881 0.84 LMNA (0.48) THRBKMT2AALDH1A1CYP1A2MEN1
SCHEMBL27739960 0.82 LMNA (0.52) THRBKMT2AALDH1A1CYP1A2MEN1
SCHEMBL29290 0.82 LMNA (0.52) THRBKMT2AALDH1A1CYP1A2MEN1
SCHEMBL10752660 0.81 KMT2A (0.37) THRBKMT2AALDH1A1CYP1A2MEN1
SCHEMBL498122 0.80 TSHR (0.55) THRBKMT2AALDH1A1MEN1LMNA
SCHEMBL31009783 0.80 TSHR (0.55) THRBKMT2AALDH1A1MEN1LMNA
SCHEMBL28977817 0.80 TSHR (0.55) THRBKMT2AALDH1A1MEN1LMNA
Pimelic Acid SCHEMBL18600626 0.80 TSHR (0.55) THRBKMT2AALDH1A1MEN1LMNA
SCHEMBL7771205 0.80 TSHR (0.55) THRBKMT2AALDH1A1MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12576169-B2 Silicon-fluoride acceptor substituted radiopharmaceuticals and precursors thereof Technische Universität München (DE) 2026-03-17 US claimed
WO-2024198046-A1 BIOMARKER AND SYSTEM FOR PREDICTING EVOLUTION INTO ACLF OR DEATH OF ACLF PATIENT, AND USES THEREOF 上海甘宁医疗科技有限公司 2024-10-03 WO claimed
US-20220096669-A1 SILICON-FLUORIDE ACCEPTOR SUBSTITUTED RADIOPHARMACEUTICALS AND PRECURSORS THEREOF Technische Universität München (DE) 2022-03-31 US claimed
EP-3917581-A1 SILICON-FLUORIDE ACCEPTOR SUBSTITUTED RADIOPHARMACEUTICALS AND PRECURSORS THEREOF Technische Universität München (DE) 2021-12-08 EP claimed
WO-2020157128-A1 SILICON-FLUORIDE ACCEPTOR SUBSTITUTED RADIOPHARMACEUTICALS AND PRECURSORS THEREOF Technische Universität München (DE) 2020-08-06 WO claimed
CN-1319618-A Holoside water retaining agent and preparation method thereof KELONGDA NEW TECHNOLOGIES APPL (CN) 2001-10-31 CN claimed
US-12576169-B2 Silicon-fluoride acceptor substituted radiopharmaceuticals and precursors thereof Technische Universität München (DE) 2026-03-17 US disclosed
CN-121538239-A Microorganism self-induction expression system without resistance gene mark and construction method thereof 安徽医科大学 2026-02-17 CN disclosed
US-12383522-B2 Baclofen formulations and methods of minimizing patient exposure to metabolite variations AMNEAL PHARMACEUTICALS LLC (US) 2025-08-12 US disclosed
CN-112165953-B Compounds useful as apelin receptor antagonists 剑桥企业有限公司 2025-03-04 CN disclosed
CN-113677375-B Silicon fluoride receptor substituted radiopharmaceuticals and precursors thereof 慕尼黑工业大学 2024-07-23 CN disclosed
CN-117980009-A Perioperative innate immunity priming in cancer therapy 曲生物制品公司 2024-05-03 CN disclosed
US-11931328-B2 Stabilized formulations of 4-amino-3-substituted butanoic acid derivatives AMNEAL PHARMACEUTICALS LLC (US) 2024-03-19 US disclosed
US-20040121316-A1 Method and compositions for identifying anti-HIV therapeutic compounds GILEAD SCIENCES, INC. 2004-06-24 US disclosed
WO-2003090690-A2 CELLULAR ACCUMULATION OF PHOSPHONATE ANALOGS OF HIV PROTEASE INHIBITOR COMPOUNDS AND THE COMPOUNDS AS SUCH GILEAD SCIENCES, INC. (US) 2003-11-06 WO disclosed
WO-2003090691-A2 METHOD AND COMPOSITIONS FOR IDENTIFYING ANTI-HIV THERAPEUTIC COMPOUNDS GILEAD SCIENCES, INC. (US) 2003-11-06 WO disclosed
WO-2003091264-A2 NON NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS GILEAD SCIENCES, INC. (US) 2003-11-06 WO disclosed
US-20030153611-A1 1,3-Diarylprop-2-en-1-ones, compositions containing them and use thereof AVENTIS PHARMA S.A. 2003-08-14 US disclosed
CN-1319618-A Holoside water retaining agent and preparation method thereof KELONGDA NEW TECHNOLOGIES APPL (CN) 2001-10-31 CN disclosed
US-3984543-A Therapeutic methods employing cyclic aminophosphonic acids HENKEL & CIE G.M.B.H. (DT) 1976-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040121316-A1 Method and compositions for identifying anti-HIV therapeutic compounds CES1, PNP, PGLS THRB 4234/4885KMT2A 4457/4885ALDH1A1 3232/4885
US-20220096669-A1 SILICON-FLUORIDE ACCEPTOR SUBSTITUTED RADIOPHARMACEUTICALS AND PRECURSORS THEREOF FOLH1, KLK3, FRS2 THRB 436/4885KMT2A 706/4885ALDH1A1 1471/4885
US-12383522-B2 Baclofen formulations and methods of minimizing patient exposure to metabolite variations GABRB1, GABRB2, GABBR1 THRB 1019/4885KMT2A 2219/4885ALDH1A1 401/4885
US-11931328-B2 Stabilized formulations of 4-amino-3-substituted butanoic acid derivatives GABRA6, GABBR1, GABBR2 THRB 3977/4885KMT2A 1038/4885ALDH1A1 250/4885
US-12576169-B2 Silicon-fluoride acceptor substituted radiopharmaceuticals and precursors thereof KLK3, FOLH1, SLC7A1 THRB 115/4885KMT2A 1100/4885ALDH1A1 2396/4885
US-20030153611-A1 1,3-Diarylprop-2-en-1-ones, compositions containing them and use thereof MCL1, ENPP1, MYC THRB 3276/4885KMT2A 2508/4885ALDH1A1 161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.