SCHEMBL349914

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27839742	0.90	P2RY6 (0.42)	ALDH1A1HSD17B10HPGDKDM4EUSP2
	SCHEMBL349148	0.77	P2RY6 (0.45)	ALDH1A1HSD17B10HPGDKDM4EUSP2
	SCHEMBL27839743	0.77	PDK1 (0.36)	ALDH1A1HSD17B10HPGDKDM4EUSP2
	SCHEMBL3284296	0.76	ALDH1A1 (0.50)	ALDH1A1HSD17B10HPGDKDM4EUSP2
	SCHEMBL9285868	0.76	TDP1 (0.53)	ALDH1A1HSD17B10HPGDKDM4EUSP2
	SCHEMBL1457185	0.76	VCAM1 (0.50)	ALDH1A1HPGDKDM4EMAPTTDP1
	SCHEMBL9060126	0.76	ALDH1A1 (0.40)	ALDH1A1HSD17B10HPGDKDM4EUSP2
	SCHEMBL348956	0.76	P2RY6 (0.41)	ALDH1A1HSD17B10HPGDKDM4EUSP2
	SCHEMBL349466	0.74	P2RY6 (0.42)	ALDH1A1HSD17B10HPGDKDM4EUSP2
	SCHEMBL14713516	0.73	TDP1 (0.52)	ALDH1A1CYP3A4MAPTTDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.