Phesa

Phesa

SCHEMBL3499217

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COS(=O)(=O)NC(=O)[C@@H](N)Cc2ccccc2)[C@@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SARS1 P49591 1/20 0.80
LARS1 Q9P2J5 2/20 0.76
HARS1 P12081 1/20 0.74
TARS1 P26639 2/20 0.74
MARS1 P56192 1/20 0.73
IARS1 P41252 1/20 0.71
RARS1 P54136 1/20 0.70
TRPM2 O94759 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phesa SCHEMBL3499221 1.00 SARS1 (0.80) SARS1LARS1HARS1TARS1MARS1
SCHEMBL4321355 0.93 SARS1 (0.79) SARS1LARS1HARS1TARS1MARS1
SCHEMBL30270578 0.89 SARS1 (0.85) SARS1LARS1HARS1TARS1MARS1
SCHEMBL21068060 0.89 SARS1 (0.87) SARS1LARS1HARS1TARS1MARS1
SCHEMBL3187665 0.89 SARS1 (0.87) SARS1LARS1HARS1TARS1MARS1
SCHEMBL3187637 0.89 SARS1 (0.87) SARS1LARS1HARS1TARS1MARS1
SCHEMBL4313369 0.89 SARS1 (1.00) SARS1LARS1HARS1TARS1MARS1
SCHEMBL21067959 0.89 SARS1 (1.00) SARS1LARS1HARS1TARS1MARS1
SCHEMBL3500697 0.88 SARS1 (0.82) SARS1LARS1HARS1TARS1MARS1
SCHEMBL178823 0.87 SARS1 (0.85) SARS1LARS1HARS1TARS1MARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121232272-A Slope instability judging method based on energy spectrum amplitude under seismic power effect 昆明理工大学 2025-12-30 CN disclosed
US-20250093263-A1 FRET-BASED ASSAYS THE GENERAL HOSPITAL CORPORATION 2025-03-20 US disclosed
EP-4374157-A2 FRET-BASED ASSAYS The General Hospital Corporation (US) 2024-05-29 EP disclosed
WO-2023004438-A2 FRET-BASED ASSAYS THE GENERAL HOSPITAL CORPORATION (US) 2023-01-26 WO disclosed
US-8778631-B2 Mono charging system for selectively introducing non-native amino acids into proteins using an in vitro protein synthesis system SUTRO BIOPHARMA, INC. (US) 2014-07-15 US disclosed
EP-2376647-B1 MONO CHARGING SYSTEM FOR SELECTIVELY INTRODUCING NON-NATIVE AMINO ACIDS INTO PROTEINS USING AN IN VITRO PROTEIN SYNTHESIS SYSTEM SUTRO BIOPHARMA INC (US) 2014-03-05 EP disclosed
US-20100184135-A1 MONO CHARGING SYSTEM FOR SELECTIVELY INTRODUCING NON-NATIVE AMINO ACIDS INTO PROTEINS USING AN IN VITRO PROTEIN SYNTHESIS SYSTEM SUTRO BIOPHARMA, INC. (US) 2010-07-22 US disclosed
US-20100184134-A1 DUAL CHARGING SYSTEM FOR SELECTIVELY INTRODUCING NON-NATIVE AMINO ACIDS INTO PROTEINS USING AN IN VITRO SYNTHESIS METHOD SUTRO BIOPHARMA, INC. (US) 2010-07-22 US disclosed
US-20100133117-A1 METHODS FOR ELECTROCHEMICAL DETECTION/QUANTIFICATION OF A NUCLEIC ACID AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-06-03 US disclosed
WO-2008097190-A1 METHODS OF ELECTRICALLY DETECTING A NUCLEIC ACID BY MEANS OF AN ELECTRODE PAIR AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2008-08-14 WO disclosed
WO-2008018833-A1 METHODS FOR ELECTROCHEMICAL DETECTION/QUANTIFICATION OF A NUCLEIC ACID AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2008-02-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250093263-A1 FRET-BASED ASSAYS TARBP1, GTPBP4, TERF2IP SARS1 12/4885LARS1 86/4885HARS1 360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.