Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 7/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.33 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3500595 | 1.00 | TBXAS1 (0.38) | TBXAS1PPARGPSEN1PSEN2APH1B | |
| SCHEMBL3503013 | 0.87 | CYP4F2 (0.40) | TBXAS1PPARGPSEN1PSEN2APH1B | |
| SCHEMBL3503011 | 0.87 | CYP4F2 (0.40) | TBXAS1PPARGPSEN1PSEN2APH1B | |
| SCHEMBL5860653 | 0.84 | TBXAS1 (0.39) | TBXAS1PPARGPSEN1PSEN2APH1B | |
| SCHEMBL31118194 | 0.82 | POLB (0.45) | PPARG | |
| SCHEMBL3501823 | 0.81 | PDE5A (0.39) | TBXAS1PPARG | |
| SCHEMBL3501826 | 0.81 | PDE5A (0.39) | TBXAS1PPARG | |
| SCHEMBL1100704 | 0.79 | TBXAS1 (0.34) | TBXAS1PPARGPSEN1PSEN2APH1B | |
| SCHEMBL1100701 | 0.79 | TBXAS1 (0.34) | TBXAS1PPARGPSEN1PSEN2APH1B | |
| SCHEMBL1587043 | 0.77 | CYP1A1 (0.46) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | GPR119, GPR65, HCAR1 | TBXAS1 2717/4885PPARG 52/4885PSEN1 4211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.