Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350072 | 1.00 | ALOX5 (0.46) | ALOX5ALDH1A1LMNAHPGDPKM | |
| SCHEMBL453156 | 0.77 | ALOX5 (0.55) | ALOX5ALDH1A1LMNAHPGDPKM | |
| SCHEMBL453158 | 0.77 | ALOX5 (0.55) | ALOX5ALDH1A1LMNAHPGDPKM | |
| SCHEMBL453157 | 0.77 | ALOX5 (0.55) | ALOX5ALDH1A1LMNAHPGDPKM | |
| SCHEMBL3009798 | 0.75 | ALOX5 (0.50) | ALOX5ALDH1A1LMNAHPGDPKM | |
| SCHEMBL348443 | 0.75 | ALOX5 (0.50) | ALOX5ALDH1A1LMNAHPGDPKM | |
| SCHEMBL4944707 | 0.75 | ALOX5 (0.50) | ALOX5ALDH1A1LMNAHPGDPKM | |
| SCHEMBL4944708 | 0.75 | ALOX5 (0.50) | ALOX5ALDH1A1LMNAHPGDPKM | |
| SCHEMBL348444 | 0.75 | ALOX5 (0.50) | ALOX5ALDH1A1LMNAHPGDPKM | |
| SCHEMBL1285898 | 0.75 | ALOX5 (0.58) | ALOX5ALDH1A1LMNAHPGDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8647882-B2 | Chiral selectors and stationary phases for separating enantiomer mixtures | EVONIK DEGUSSA GMBH (DE) | 2014-02-11 | — | — | US | disclosed |
| US-20120015443-A1 | NOVEL CHIRAL SELECTORS AND STATIONARY PHASES FOR SEPARATING ENANTIOMER MIXTURES | EVONIK DEGUSSA GMBH (DE) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015443-A1 | NOVEL CHIRAL SELECTORS AND STATIONARY PHASES FOR SEPARATING ENANTIOMER MIXTURES | BCAT2, BCAT1, SLC43A1 | ALOX5 4649/4885ALDH1A1 1107/4885LMNA 2351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.