SCHEMBL3501859

SCHEMBL3501859

O=C(C=CC1=C(O)CC(O)(O)C=C1O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.47
MAOB P27338 4/20 0.47
LMNA P02545 3/20 0.47
BCHE P06276 3/20 0.47
CYP1B1 Q16678 2/20 0.47
PLIN1 O60240 1/20 0.47
TNFRSF1A P19438 1/20 0.47
ACHE P22303 1/20 0.47
RECQL P46063 1/20 0.47
PLIN5 Q00G26 1/20 0.47
ABHD5 Q8WTS1 1/20 0.47
CYP3A4 P08684 4/20 0.46
RAB9A P51151 4/20 0.46
NFKB1 P19838 3/20 0.46
NFKB2 Q00653 3/20 0.46
RELA Q04206 3/20 0.46
HSPD1 P10809 2/20 0.46
HSPE1 P61604 2/20 0.46
KMT2A Q03164 2/20 0.46
PKM P14618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6270921 0.75 MAPT (0.46) MAPTMAOBLMNABCHECYP1B1
SCHEMBL372313 0.74 MAPT (0.45) MAPTMAOBLMNABCHECYP1B1
SCHEMBL6364835 0.71 MAPT (0.47) MAPTMAOBLMNABCHECYP1B1
SCHEMBL2169161 0.71 TRPA1 (0.44) MAPTLMNABCHENFKB1KMT2A
Chalcone SCHEMBL27566080 0.68 CYP1B1 (0.96) MAPTMAOBLMNABCHECYP1B1
Chalcone SCHEMBL27991152 0.68 CYP1B1 (0.96) MAPTMAOBLMNABCHECYP1B1
SCHEMBL2954318 0.67 MAPT (0.70) MAPTMAOBLMNABCHECYP1B1
SCHEMBL2954324 0.67 MAPT (0.70) MAPTMAOBLMNABCHECYP1B1
SCHEMBL11073619 0.67 MAPT (0.70) MAPTMAOBLMNABCHECYP1B1
Chalcone SCHEMBL27581 0.66 CYP1B1 (1.00) MAPTMAOBLMNABCHECYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100199370-A1 MEANS AND METHODS OF PRODUCING FRUITS WITH HIGH LEVELS OF ANTHOCYANINS AND FLAVONOLS The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research 2010-08-05 US claimed
EP-2131646-A2 MEANS AND METHODS OF PRODUCING FRUITS WITH HIGH LEVELS OF ANTHOCYANINS AND FLAVONOLS The State of Israel, Ministry of Agriculture and Rural Development, Agricultural Research Organisation, Volcani Center (IL) 2009-12-16 EP claimed
WO-2008096354-A2 MEANS AND METHODS OF PRODUCING FRUITS WITH HIGH LEVELS OF ANTHOCYANINS AND FLAVONOLS THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION, (A.R.O.), THE VOLCANL CENTER (IL) 2008-08-14 WO claimed
US-20100199370-A1 MEANS AND METHODS OF PRODUCING FRUITS WITH HIGH LEVELS OF ANTHOCYANINS AND FLAVONOLS The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research 2010-08-05 US disclosed
EP-2131646-A2 MEANS AND METHODS OF PRODUCING FRUITS WITH HIGH LEVELS OF ANTHOCYANINS AND FLAVONOLS The State of Israel, Ministry of Agriculture and Rural Development, Agricultural Research Organisation, Volcani Center (IL) 2009-12-16 EP disclosed
WO-2008096354-A2 MEANS AND METHODS OF PRODUCING FRUITS WITH HIGH LEVELS OF ANTHOCYANINS AND FLAVONOLS THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION, (A.R.O.), THE VOLCANL CENTER (IL) 2008-08-14 WO disclosed
EP-1054986-B1 ISOLATED AND PURIFIED NUCLEIC ACIDS COMPRISING A GENE SPECIFICALLY EXPRESSED IN HOP GLANDS SAPPORO BREWERIES (JP) 2007-10-31 EP disclosed
US-7060815-B2 Isolated and purified nucleic acids comprising a gene and a regulatory region for the gene expression of the same SAPPORO BREWERIES LTD. (JP) 2006-06-13 US disclosed
US-6639127-B2 Nucleotide sequences coding plant protein; for use in hop culturing SAPPORO BREWERIES LTD. (JP) 2003-10-28 US disclosed
US-20030192071-A1 Isolated and purified nucleic acids comprising a gene and a regulatory region for the gene expression of the same SAPPORO BREWERIES LIMITED (JP) 2003-10-09 US disclosed
US-20020010952-A1 Isolated and purified nucleic acids comprising a gene and a regulatory region for the gene expression of the same SAPPORO BREWERIES LTD. (JP) 2002-01-24 US disclosed
US-6265633-B1 NUCLEOTIDE SEQUENCES WHICH CODE GENE PRODUCT ASSOCIATED WITH HOPS; FOR AMPLIFIED QUALITY FOR BEER BREWING AND FOR USE IN GENERATING THERAPEUTICS SAPPORO BREWERIES LTD. (JP) 2001-07-24 US disclosed
EP-1054986-A1 ISOLATED AND PURIFIED NUCLEIC ACIDS COMPRISING A GENE SPECIFICALLY EXPRESSED IN HOP GLANDS SAPPORO BREWERIES LTD. (JP) 2000-11-29 EP disclosed
WO-1999042599-A1 ISOLATED AND PURIFIED NUCLEIC ACIDS COMPRISING A GENE SPECIFICALLY EXPRESSED IN HOP GLANDS SAPPORO BREWERIES LTD. (JP) 1999-08-26 WO disclosed