Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.45 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.45 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.45 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.44 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28132376 | 0.75 | MAPT (0.45) | MAPTMAOBLMNABCHECYP1B1 | |
| SCHEMBL28022175 | 0.75 | MAPT (0.41) | MAPTMAOBLMNABCHECYP1B1 | |
| SCHEMBL3501859 | 0.74 | MAPT (0.47) | MAPTMAOBLMNABCHECYP1B1 | |
| SCHEMBL3503674 | 0.69 | MAPT (0.43) | MAPTMAOBLMNABCHECYP1B1 | |
| SCHEMBL13203533 | 0.66 | CYP1B1 (0.80) | MAPTMAOBLMNABCHECYP1B1 | |
| SCHEMBL11073619 | 0.65 | MAPT (0.70) | MAPTMAOBLMNABCHECYP1B1 | |
| SCHEMBL2954318 | 0.65 | MAPT (0.70) | MAPTMAOBLMNABCHECYP1B1 | |
| SCHEMBL2954324 | 0.65 | MAPT (0.70) | MAPTMAOBLMNABCHECYP1B1 | |
| Chalcone SCHEMBL454583 | 0.64 | CYP1B1 (1.00) | MAPTMAOBLMNABCHECYP1B1 | |
| Chalcone SCHEMBL27581 | 0.64 | CYP1B1 (1.00) | MAPTMAOBLMNABCHECYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140308376-A1 | Cosmetic Compositions and Methods for Using Same to Improve the Aesthetic Appearance of Skin | AVON PRODUCTS, INC. | 2014-10-16 | — | — | US | claimed |
| US-20120315344-A1 | Cosmetic Compositions and Methods for Using Same to Improve the Aesthetic Appearance of Skin | AVON PRODUCTS, INC. (US) | 2012-12-13 | — | — | US | claimed |
| EP-2409681-A1 | Method for improving the aesthetic appearance of skin by enhancing the skin thickness | AVON PRODUCTS, INC. (US) | 2012-01-25 | — | — | EP | claimed |
| EP-1622579-B1 | COSMETIC COMPOSITIONS AND METHODS FOR USING SAME TO IMPROVE THE AESTHETIC APPEARANCE OF SKIN | AVON PROD INC (US) | 2011-03-30 | — | — | EP | claimed |
| EP-1622579-A4 | COSMETIC COMPOSITIONS AND METHODS FOR USING SAME TO IMPROVE THE AESTHETIC APPEARANCE OF SKIN | AVON PROD INC (US) | 2007-12-12 | — | — | EP | claimed |
| EP-1622579-A2 | COSMETIC COMPOSITIONS AND METHODS FOR USING SAME TO IMPROVE THE AESTHETIC APPEARANCE OF SKIN | Avon Products, Inc. (US) | 2006-02-08 | — | — | EP | claimed |
| WO-2004100889-A2 | COSMETIC COMPOSITIONS AND METHODS FOR USING SAME TO IMPROVE THE AESTHETIC APPEARANCE OF SKIN | AVON PRODUCTS, INC. (US) | 2004-11-25 | — | — | WO | claimed |
| US-20040067245-A1 | Containing 3,3'-thiodipropionic acid or an ester of it | AVON PRODUCTS, INC. | 2004-04-08 | — | — | US | claimed |
| US-20140308376-A1 | Cosmetic Compositions and Methods for Using Same to Improve the Aesthetic Appearance of Skin | AVON PRODUCTS, INC. | 2014-10-16 | — | — | US | disclosed |
| US-8808765-B2 | Cosmetic compositions and methods for using same to improve the aesthetic appearance of skin | AVON PRODUCTS, INC (US) | 2014-08-19 | — | — | US | disclosed |
| US-20120315344-A1 | Cosmetic Compositions and Methods for Using Same to Improve the Aesthetic Appearance of Skin | AVON PRODUCTS, INC. (US) | 2012-12-13 | — | — | US | disclosed |
| EP-2409681-A1 | Method for improving the aesthetic appearance of skin by enhancing the skin thickness | AVON PRODUCTS, INC. (US) | 2012-01-25 | — | — | EP | disclosed |
| EP-1622579-B1 | COSMETIC COMPOSITIONS AND METHODS FOR USING SAME TO IMPROVE THE AESTHETIC APPEARANCE OF SKIN | AVON PROD INC (US) | 2011-03-30 | — | — | EP | disclosed |
| EP-1622579-A4 | COSMETIC COMPOSITIONS AND METHODS FOR USING SAME TO IMPROVE THE AESTHETIC APPEARANCE OF SKIN | AVON PROD INC (US) | 2007-12-12 | — | — | EP | disclosed |
| EP-1622579-A2 | COSMETIC COMPOSITIONS AND METHODS FOR USING SAME TO IMPROVE THE AESTHETIC APPEARANCE OF SKIN | Avon Products, Inc. (US) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004100889-A2 | COSMETIC COMPOSITIONS AND METHODS FOR USING SAME TO IMPROVE THE AESTHETIC APPEARANCE OF SKIN | AVON PRODUCTS, INC. (US) | 2004-11-25 | — | — | WO | disclosed |
| US-20040067245-A1 | Containing 3,3'-thiodipropionic acid or an ester of it | AVON PRODUCTS, INC. | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140308376-A1 | Cosmetic Compositions and Methods for Using Same to Improve the Aesthetic Appearance of Skin | CUTA, GLA, TYR | MAPT 2597/4885MAOB 581/4885LMNA 1165/4885 |
| US-20120315344-A1 | Cosmetic Compositions and Methods for Using Same to Improve the Aesthetic Appearance of Skin | CUTA, GLA, ALAD | MAPT 3237/4885MAOB 2223/4885LMNA 3246/4885 |
| US-20040067245-A1 | Containing 3,3'-thiodipropionic acid or an ester of it | PPARG, PPARA, TYR | MAPT 2231/4885MAOB 2941/4885LMNA 3992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.