Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | GGT1 | P19440 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8850933 | 0.97 | KDM4E (0.54) | KDM4EHSD17B10HPGDMAPTKMT2A | |
| SCHEMBL17926777 | 0.85 | KDM4E (0.59) | KDM4EHSD17B10HPGDMAPTKMT2A | |
| Diaspirin SCHEMBL30735506 | 0.80 | KDM4E (0.75) | KDM4EHSD17B10HPGDMAPTKMT2A | |
| Diaspirin SCHEMBL40799 | 0.80 | KDM4E (0.75) | KDM4EHSD17B10HPGDMAPTKMT2A | |
| SCHEMBL844727 | 0.80 | KDM4E (0.70) | KDM4EHSD17B10HPGDMAPTKMT2A | |
| SCHEMBL31265186 | 0.79 | KDM4E (0.63) | KDM4EHSD17B10HPGDMAPTKMT2A | |
| SCHEMBL31265184 | 0.79 | KDM4E (0.63) | KDM4EHSD17B10HPGDMAPTKMT2A | |
| SCHEMBL16800472 | 0.79 | KDM4E (0.63) | KDM4EHSD17B10HPGDMAPTKMT2A | |
| SCHEMBL8436639 | 0.79 | KDM4E (0.63) | KDM4EHSD17B10HPGDMAPTKMT2A | |
| SCHEMBL14010487 | 0.78 | ALDH1A1 (0.52) | KDM4EHSD17B10HPGDMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8227418-B2 | Alpha-defensins as anthrax immunotherapeutics | MAX-PLANCK-GESELLSCHAFT ZUR FODERUNG DER WISSENSCHAFTEN E.V. (DE) | 2012-07-24 | — | — | US | claimed |
| US-20100143416-A1 | Alpha-defensins as anthrax immunotherapeutis | MAX-PLANCK GESELLSCHAFT ZUR FODERUNG DER WISSENSCHAFTEN E.V. | 2010-06-10 | — | — | US | claimed |
| EP-1786453-B1 | ALPHA-DEFENSINS AS ANTHRAX IMMUNOTHERAPEUTICS | MAX PLANCK GESELLSCHAFT (DE) | 2009-01-14 | — | — | EP | claimed |
| EP-1786453-A1 | ALPHA-DEFENSINS AS ANTHRAX IMMUNOTHERAPEUTICS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2007-05-23 | — | — | EP | claimed |
| WO-2006008162-A1 | ALPHA-DEFENSINS AS ANTHRAX IMMUNOTHERAPEUTICS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2006-01-26 | — | — | WO | claimed |
| JP-8113553-A | — | — | None | — | — | JP | disclosed |
| JP-8291138-A | — | — | None | — | — | JP | disclosed |
| JP-8209195-A | — | — | None | — | — | JP | disclosed |
| US-8227418-B2 | Alpha-defensins as anthrax immunotherapeutics | MAX-PLANCK-GESELLSCHAFT ZUR FODERUNG DER WISSENSCHAFTEN E.V. (DE) | 2012-07-24 | — | — | US | disclosed |
| US-20100143416-A1 | Alpha-defensins as anthrax immunotherapeutis | MAX-PLANCK GESELLSCHAFT ZUR FODERUNG DER WISSENSCHAFTEN E.V. | 2010-06-10 | — | — | US | disclosed |
| EP-1786453-B1 | ALPHA-DEFENSINS AS ANTHRAX IMMUNOTHERAPEUTICS | MAX PLANCK GESELLSCHAFT (DE) | 2009-01-14 | — | — | EP | disclosed |
| EP-1539132-A4 | USE OF 2,3 ALKYLCARBONYLOXYBENZOIC ACIDS, DERIVATIVES AND ANALOGUES THEREFROM IN THE TREATMENT OF TISSUE AND CELLULAR DYSFUNCTION DAMAGE AND INJURY IN MAMMALS | ADVANCED LIFE SCIENCES INC (US) | 2007-10-31 | — | — | EP | disclosed |
| EP-0572227-B1 | Use of an emulsion of a polymer comprising (meth)acrylate units as a dental adhesive | MITSUI CHEMICALS INC (JP) | 2000-08-23 | — | — | EP | disclosed |
| US-5629361-A | ANTIHYPERSENSITIVE FILMS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-05-13 | — | — | US | disclosed |
| JP-H08291138-A | ANTIFERROELECTRIC LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | SHOWA SHELL SEKIYU KK | 1996-11-05 | — | — | JP | disclosed |
| US-5554669-A | DENTAL ADHESIVES | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-10 | — | — | US | disclosed |
| JP-H08209195-A | PRODUCTION OF GRANULATED BLEACHING ACTIVATOR | LION CORP | 1996-08-13 | — | — | JP | disclosed |
| JP-H08113553-A | STRONG ANTIFERROELECTRIC LIQUID CRYSTAL COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | SHOWA SHELL SEKIYU KK | 1996-05-07 | — | — | JP | disclosed |
| US-5504111-A | Use of 2,3 alkylcarbonyloxybenzoic acid in treating adult respiratory distress syndrome | MEDICHEM RESEARCH, INC. (US) | 1996-04-02 | — | — | US | disclosed |
| EP-0572227-A1 | Polymer having (meth)acrylate unit, emulsion thereof, processes for their productions, and adhesive compositions containing the emulsion | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |