Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.61 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | GGT1 | P19440 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844727 | 0.86 | KDM4E (0.70) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| Diaspirin SCHEMBL30735506 | 0.86 | KDM4E (0.75) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| Diaspirin SCHEMBL40799 | 0.86 | KDM4E (0.75) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL1358287 | 0.85 | KDM4E (0.59) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL14494719 | 0.85 | KDM4E (0.69) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| Bromoaspirin SCHEMBL6691615 | 0.83 | KDM4E (0.61) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL6129343 | 0.83 | KDM4E (0.61) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL4401026 | 0.83 | KDM4E (0.61) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL13006825 | 0.83 | KDM4E (0.72) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL2763226 | 0.83 | KDM4E (0.71) | KDM4EKMT2AMEN1RECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111727041-A | Composition for treating non-alcoholic fatty liver disease and non-alcoholic steatohepatitis | 卢莫斯制药公司 | 2020-09-29 | — | — | CN | disclosed |
| EP-0732322-B1 | Acetylsalicylic acid derivatives having a vinyl group | UBE INDUSTRIES (JP) | 1999-12-22 | — | — | EP | disclosed |
| US-5693320-A | ANTICOAGULANTS, BIOCOMPATIBILITY, MEDICAL EQUIPMENT | UBE INDUSTRIES, LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0732322-A1 | Acetylsalicylic acid derivatives having a vinyl group | UBE INDUSTRIES, LTD. (JP) | 1996-09-18 | — | — | EP | disclosed |