Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.70 |
| ▸ | HPGD | P15428 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.63 |
| ▸ | ESR1 | P03372 | 1/20 | 0.63 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.63 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.63 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | GGT1 | P19440 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844726 | 0.92 | KDM4E (0.66) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL17787232 | 0.91 | KDM4E (0.60) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL11065761 | 0.89 | KDM4E (0.67) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| Diaspirin SCHEMBL40799 | 0.88 | KDM4E (0.75) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| Diaspirin SCHEMBL30735506 | 0.88 | KDM4E (0.75) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL8436639 | 0.86 | KDM4E (0.63) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL27145067 | 0.86 | KDM4E (0.58) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL13006825 | 0.85 | KDM4E (0.72) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| Bromoaspirin SCHEMBL6691615 | 0.85 | KDM4E (0.61) | KDM4EHSD17B10HPGDKMT2AMEN1 | |
| SCHEMBL4401026 | 0.85 | KDM4E (0.61) | KDM4EHSD17B10HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9011734-B2 | Ligand exchange thermochromic, (LETC), systems | PLEOTINT, L.L.C. (US) | 2015-04-21 | — | — | US | claimed |
| US-8018639-B2 | Ligand exchange thermochromic, (LETC), systems | PLEOTINT, L.L.C. (US) | 2011-09-13 | — | — | US | claimed |
| US-20090283728-A1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | PLEOTINT, LLC (US) | 2009-11-19 | — | — | US | claimed |
| EP-2082005-A1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | Pleotint, L.L.C. (US) | 2009-07-29 | — | — | EP | claimed |
| US-20080100902-A1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | PLEOTINT, LLC (US) | 2008-05-01 | — | — | US | claimed |
| WO-2008028128-A1 | LIGAND EXCHANGE THERMOCHROMIC, (LETC), SYSTEMS | PLEOTINT, L.L.C. (US) | 2008-03-06 | — | — | WO | claimed |
| US-9782432-B2 | Polymers and methods thereof for wound healing | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-10-10 | — | — | US | disclosed |
| US-20160175343-A1 | POLYMERS AND METHODS THEREOF FOR WOUND HEALING | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-06-23 | — | — | US | disclosed |
| US-9351980-B2 | Di-aspirin derivatives | THE UNIVERSITY OF WOLVERHAMPTON (GB) | 2016-05-31 | — | — | US | disclosed |
| US-9351980-B2 | Di-aspirin derivatives | THE UNIVERSITY OF WOLVERHAMPTON (GB) | 2016-05-31 | — | — | US | disclosed |
| US-20140120057-A1 | POLYMERS AND METHODS THEREOF FOR WOUND HEALING | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-05-01 | — | — | US | disclosed |
| US-20130035317-A1 | Di-Aspirin Derivatives | THE UNIVERISTY OF WOLVERHAMPTON (GB) | 2013-02-07 | — | — | US | disclosed |
| US-20130022569-A1 | HYDROGELS | NIH - DEITR | 2013-01-24 | — | — | US | disclosed |
| US-20130022569-A1 | HYDROGELS | NIH - DEITR | 2013-01-24 | — | — | US | disclosed |
| EP-2436750-A2 | Ligand exchange thermochromic, (LETC), systems | Pleotint, L.L.C. (US) | 2012-04-04 | — | — | EP | disclosed |
| EP-2434000-A2 | Ligand exchange thermochromic, (LETC), systems | Pleotint, L.L.C. (US) | 2012-03-28 | — | — | EP | disclosed |
| WO-2011098839-A2 | DI-ASPIRIN DERIVATIVES | THE UNIVERSITY OF WOLVERHAMPTON (GB) | 2011-08-18 | — | — | WO | disclosed |
| US-20090196928-A1 | Biocompatible hydrogel compositions | HNOJEWYI OLEXANDER | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160175343-A1 | POLYMERS AND METHODS THEREOF FOR WOUND HEALING | COL1A1, FGB, CD68 | KDM4E 1543/4885HSD17B10 2079/4885HPGD 318/4885 |
| US-20090196928-A1 | Biocompatible hydrogel compositions | CRYAA, AADAC, CD44 | KDM4E 3941/4885HSD17B10 1875/4885HPGD 907/4885 |
| US-20130022569-A1 | HYDROGELS | PUF60, EPAS1, EGLN3 | KDM4E 1634/4885HSD17B10 1017/4885HPGD 818/4885 |
| US-20140120057-A1 | POLYMERS AND METHODS THEREOF FOR WOUND HEALING | COL1A1, FGB, CD68 | KDM4E 1543/4885HSD17B10 2079/4885HPGD 318/4885 |
| US-20130035317-A1 | Di-Aspirin Derivatives | SDHA, DLD, DPYD | KDM4E 2764/4885HSD17B10 987/4885HPGD 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.