Dihydroactinidiolide

Dihydroactinidiolide

SCHEMBL3503557

CC1(C)CCCC2(C)OC(=O)C=C12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ACHE P22303 1/20 1.00
▸ POLB P06746 2/20 0.36
▸ CACNA1G O43497 1/20 0.35
▸ ALOX12 P18054 2/20 0.35
▸ ALOX5 P09917 1/20 0.35
▸ ALOX15 P16050 1/20 0.35
▸ ALDH1A1 P00352 7/20 0.33
▸ HPGD P15428 2/20 0.33
▸ KMT2A Q03164 2/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ HTT P42858 1/20 0.30
▸ KDM4E B2RXH2 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ CES2 O00748 1/20 0.30
▸ APAF1 O14727 1/20 0.30
▸ TERT O14746 1/20 0.30
▸ EED O75530 1/20 0.30
▸ LMNA P02545 1/20 0.30
▸ TP53 P04637 1/20 0.30
▸ MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
D-Dihydroactinidiolide SCHEMBL2186328 1.00 ACHE (1.00) ACHEPOLBCACNA1GALOX12ALOX5
SCHEMBL19361160 0.77 ACHE (0.62) ACHECACNA1G
SCHEMBL4394665 0.72 ACHE (0.56) ACHECACNA1G
SCHEMBL12244572 0.71 ACHE (0.54) ACHECES1
SCHEMBL14813240 0.71 ALOX15 (0.68) ACHEALOX12ALOX5ALOX15ALDH1A1
SCHEMBL20319945 0.69 ACHE (0.53) ACHE
Loliolide SCHEMBL10181773 0.69 ACHE (0.53) ACHE
Loliolide SCHEMBL16057196 0.69 ACHE (0.53) ACHE
Loliolide SCHEMBL789415 0.69 ACHE (0.53) ACHE
Loliolide SCHEMBL12939655 0.69 ACHE (0.53) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119925344-A Application of telalactone in preparing medicament for inhibiting tumor angiogenesis 山东大学 2025-05-06 — — CN claimed
US-20240306688-A1 METHOD OF MITIGATING OFF-ODORS GIVAUDAN SA (CH) 2024-09-19 — — US claimed
EP-4391827-A1 METHOD OF MITIGATING OFF-ODORS Givaudan SA (CH) 2024-07-03 — — EP claimed
US-20230301329-A1 COMPOSITIONS COMPRISING COOLNESS-REGULATING AGENT, AND METHOD OF USE THEREOF EPC NATURAL PRODUCTS CO., LTD. (CN) 2023-09-28 — — US claimed
US-11751593-B2 Sweetener and flavor compositions, methods of making and methods of use thereof EPC Natural Products Co., Ltd (CN) 2023-09-12 — — US claimed
WO-2023025549-A1 METHOD OF MITIGATING OFF-ODORS GIVAUDAN SA (CH) 2023-03-02 — — WO claimed
CN-111189945-B Separation method of tea aroma components in tea de-enzyming substances of Tieguanyin tea 福建中烟工业有限责任公司 2022-09-30 — — CN claimed
US-20210386104-A1 WATER SOLUBLE FLAVOR COMPOSITIONS, METHODS OF MAKING AND METHODS OF USE THEREOF EPC Natural Products Co., Ltd (CN) 2021-12-16 — — US claimed
US-20200138071-A1 SWEETENER AND FLAVOR COMPOSITIONS, METHODS OF MAKING AND METHODS OF USE THEREOF EPC Natural Products Co., Ltd (CN) 2020-05-07 — — US claimed
CN-120064508-A Method for constructing Tianming extract fingerprint 湖南中医药大学 2025-05-30 — — CN disclosed
WO-2025106614-A1 COMPOSITIONS COMPRISING ULTRAFINE BUBBLES AND METHODS OF USING THEREOF IN AGRICULTURE HYDROSOME IP, LLC (US) 2025-05-22 — — WO disclosed
CN-119925344-A Application of telalactone in preparing medicament for inhibiting tumor angiogenesis 山东大学 2025-05-06 — — CN disclosed
CN-119925344-A Application of telalactone in preparing medicament for inhibiting tumor angiogenesis 山东大学 2025-05-06 — — CN disclosed
CN-119925344-A Application of telalactone in preparing medicament for inhibiting tumor angiogenesis 山东大学 2025-05-06 — — CN disclosed
CN-106999972-A System and method for discharging fragrance 阿甘芳香和精细化工有限公司 2017-08-01 — — CN disclosed
CN-103226136-B Detection and determination method for flavor type of cigarette HONGTA TOBACCO GROUP CO LTD 2014-12-03 — — CN disclosed
US-8609600-B2 Encapsulation of bulky fragrance molecules TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-12-17 — — US disclosed
CN-103226136-A Detection and determination method for flavor type of cigarette HONGTA TOBACCO GROUP CO LTD 2013-07-31 — — CN disclosed
US-20100248390-A1 COMPOSITIONS AND METHODS FOR IDENTIFYING LIGANDS OF ODORANT RECEPTORS DUKE UNIVERSITY (US) 2010-09-30 — — US disclosed
US-20080176780-A1 ENCAPSULATION OF BULKY FRAGRANCE MOLECULES TAKASAGO INTERNATIONAL CORPORATION (JP) 2008-07-24 — — US disclosed
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