D-Dihydroactinidiolide

D-Dihydroactinidiolide

SCHEMBL2186328

CC1(C)CCC[C@@]2(C)OC(=O)C=C12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ACHE P22303 1/20 1.00
▸ POLB P06746 2/20 0.36
▸ CACNA1G O43497 1/20 0.35
▸ ALOX12 P18054 2/20 0.35
▸ ALOX5 P09917 1/20 0.35
▸ ALOX15 P16050 1/20 0.35
▸ ALDH1A1 P00352 7/20 0.33
▸ HPGD P15428 2/20 0.33
▸ KMT2A Q03164 2/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ HTT P42858 1/20 0.30
▸ KDM4E B2RXH2 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ CES2 O00748 1/20 0.30
▸ APAF1 O14727 1/20 0.30
▸ TERT O14746 1/20 0.30
▸ EED O75530 1/20 0.30
▸ LMNA P02545 1/20 0.30
▸ TP53 P04637 1/20 0.30
▸ MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dihydroactinidiolide SCHEMBL3503557 1.00 ACHE (1.00) ACHEPOLBCACNA1GALOX12ALOX5
SCHEMBL19361160 0.77 ACHE (0.62) ACHECACNA1G
SCHEMBL4394665 0.72 ACHE (0.56) ACHECACNA1G
SCHEMBL12244572 0.71 ACHE (0.54) ACHECES1
SCHEMBL14813240 0.71 ALOX15 (0.68) ACHEALOX12ALOX5ALOX15ALDH1A1
SCHEMBL20319945 0.69 ACHE (0.53) ACHE
Loliolide SCHEMBL10181773 0.69 ACHE (0.53) ACHE
Loliolide SCHEMBL16057196 0.69 ACHE (0.53) ACHE
Loliolide SCHEMBL789415 0.69 ACHE (0.53) ACHE
Loliolide SCHEMBL12939655 0.69 ACHE (0.53) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1678 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014065-A1 PHYTOCHEMICAL INFUSED COSMETIC COMPOSITIONS AND THERAPEUTIC USES THEREOF Dewey Beauty LLC (US) 2026-01-15 — — US claimed
US-20250113855-A1 HYDRATING AND REHYDRATING COMPOSITOIN AND PRODUCT IV THOUGHT PRODUCTS AND DESIGN CORP. 2025-04-10 — — US claimed
US-20240400784-A1 Method for Screening Solvent for Extracting Polyvinyl Chloride, Method for Recycling Waste, Recycled Polyvinyl Chloride, and Composition LG CHEM, LTD. (KR) 2024-12-05 — — US claimed
US-20240392094-A1 Method for Screening Solvent for Polyvinyl Chloride Extraction, Recycling Method for Waste Material, and Recycled Polyvinyl Chloride and Composition LG CHEM, LTD. (KR) 2024-11-28 — — US claimed
US-12016358-B2 Composition comprising taste modulation compounds, their use and foodstuff comprising them V. MANE FILS (FR) 2024-06-25 — — US claimed
WO-2024124354-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING PAIN OR OTHER DISORDERS AIMA INC. (CA) 2024-06-20 — — WO claimed
US-20230338329-A1 CANNABINOID EMULSION COMPOSITION AND METHOD OF MANUFACTURING GORE DOUGLAS (US) 2023-10-26 — — US claimed
EP-4085769-B1 METHOD FOR IMPROVING AROMA OF CIGARETTE PRODUCT BY USING RASPBERRY KETONE GLUCOSIDE CHINA TOBACCO YUNNAN IND CO LTD (CN) 2023-09-20 — — EP claimed
WO-2023108277-A1 CANNABINOID AND PSYCHEDELIC FORMULATIONS COMPRISING HYDROTROPIC AGENTS AGILE PHARMACEUTICALS SOLUTIONS INC. (CA) 2023-06-22 — — WO claimed
US-11632973-B2 Composition comprising taste modulation compounds, their use and foodstuff comprising them V. MANE FILS (FR) 2023-04-25 — — US claimed
US-7105628-B2 Compositions for golf equipment ACUSHNET COMPANY (US) 2006-09-12 — — US claimed
WO-2006034570-A1 COMPOSITIONS AND METHODS FOR PROMOTING WEIGHT GAIN AND FEED CONVERSION CHEMAPHOR INC. (CA) 2006-04-06 — — WO claimed
US-20050238738-A1 Methods for deriving, isolating, and/or extracting amino acid compositions from Fenugreek seed TSI GROUP LIMITED (HK) 2005-10-27 — — US claimed
US-20050226948-A1 Methods for enhancing the transport of glucose into muscle TECHNICAL SOURCING INTERNATIONAL, INC. 2005-10-13 — — US claimed
WO-2005084323-A2 COMPOSITIONS OF BIO-ACTIVE COMPOUNDS FROM FENUGREEK SEED AND METHODS FOR PRODUCING SAME TECHNICAL SOURCING INTERNATIONAL, INC. (US) 2005-09-15 — — WO claimed
US-20040220378-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 — — US claimed
CN-1182084-A Synthesis and application of dihydro-actinidia lactone CHEN YONGKUAN (CN) 1998-05-20 — — CN claimed
US-5705372-A Enzymatic process for the preparation of flavours, in particular the ionones and C6 to C10 aldehydes BFA LABORATORIES (FR) 1998-01-06 — — US claimed
EP-0662141-A1 METHOD FOR THE ENZYMATIC PREPARATION OF AROMAS, PARTICULARLY IONONS AND C 6 TO C 10 ALDEHYDES BFA LABORATOIRES (FR) 1995-07-12 — — EP claimed
WO-1994008028-A1 METHOD FOR THE ENZYMATIC PREPARATION OF AROMAS, PARTICULARLY IONONS AND C6 TO C10 ALDEHYDES BFA LABORATOIRES (FR) 1994-04-14 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050226948-A1 Methods for enhancing the transport of glucose into muscle GYS1, SLC2A3, MUSK ACHE 313/4885POLB 2665/4885CACNA1G 3141/4885
US-20050238738-A1 Methods for deriving, isolating, and/or extracting amino acid compositions from Fenugreek seed SHBG, SIK3, HGFAC ACHE 495/4885POLB 2436/4885CACNA1G 3595/4885
US-20260014065-A1 PHYTOCHEMICAL INFUSED COSMETIC COMPOSITIONS AND THERAPEUTIC USES THEREOF DHCR24, CNR2, DSG1 ACHE 580/4885POLB 1278/4885CACNA1G 1513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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