Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16130557 | 0.78 | CHRNB2 (0.55) | NUDT1BACE1PIK3C3NR3C2MEN1 | |
| SCHEMBL18713207 | 0.78 | NUDT1 (0.42) | NUDT1BACE1PIK3C3NR3C2RIPK1 | |
| SCHEMBL2606087 | 0.78 | CHRNB2 (0.55) | NUDT1BACE1PIK3C3NR3C2MEN1 | |
| SCHEMBL16130585 | 0.78 | CHRNB2 (0.55) | NUDT1BACE1PIK3C3NR3C2MEN1 | |
| SCHEMBL13104784 | 0.77 | P2RX7 (0.43) | NUDT1BACE1PIK3C3NR3C2RIPK1 | |
| SCHEMBL15273881 | 0.77 | P2RX7 (0.43) | NUDT1BACE1PIK3C3NR3C2RIPK1 | |
| SCHEMBL27364822 | 0.77 | BACE1 (0.53) | BACE1PIK3C3NR3C2RIPK1SCD5 | |
| SCHEMBL14829587 | 0.77 | BACE1 (0.53) | BACE1PIK3C3NR3C2RIPK1POLB | |
| Bromide SCHEMBL5224743 | 0.76 | CHRNB2 (0.53) | NUDT1BACE1PIK3C3NR3C2MEN1 | |
| SCHEMBL27331726 | 0.76 | NR3C2 (0.54) | NUDT1PIK3C3NR3C2LMNAHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015947-A1 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2012-01-19 | — | — | US | disclosed |
| US-20120015947-A1 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2012-01-19 | — | — | US | disclosed |
| US-20120015947-A1 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2012-01-19 | — | — | US | disclosed |
| US-8053432-B2 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2011-11-08 | — | — | US | disclosed |
| US-8053432-B2 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2011-11-08 | — | — | US | disclosed |
| US-8053432-B2 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2011-11-08 | — | — | US | disclosed |
| US-7842690-B2 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2010-11-30 | — | — | US | disclosed |
| US-7842689-B2 | suitable for the treatment of anxiety and depression; 2-(4-hydroxymorpholin-3-yl)cyclohex-2-en-1-one; anxiolytic agents; antidepressants | BTG INTERNATIONAL LIMITED (GB) | 2010-11-30 | — | — | US | disclosed |
| US-7842689-B2 | suitable for the treatment of anxiety and depression; 2-(4-hydroxymorpholin-3-yl)cyclohex-2-en-1-one; anxiolytic agents; antidepressants | BTG INTERNATIONAL LIMITED (GB) | 2010-11-30 | — | — | US | disclosed |
| US-7842689-B2 | suitable for the treatment of anxiety and depression; 2-(4-hydroxymorpholin-3-yl)cyclohex-2-en-1-one; anxiolytic agents; antidepressants | BTG INTERNATIONAL LIMITED (GB) | 2010-11-30 | — | — | US | disclosed |
| CN-1805944-B | Cyclic hydroxylamine as psychoactive compounds | BRITISH TECH GROUP INT | 2010-06-16 | — | — | CN | disclosed |
| US-20090312329-A1 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2009-12-17 | — | — | US | disclosed |
| US-20090312329-A1 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2009-12-17 | — | — | US | disclosed |
| US-20090312329-A1 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2009-12-17 | — | — | US | disclosed |
| EP-1631557-B1 | CYCLIC HYDROXYLAMINE AS PSYCHOACTIVE COMPOUNDS | BTG INT LTD (GB) | 2006-12-20 | — | — | EP | disclosed |
| CN-1805944-A | Cyclic hydroxylamine as psychoactive compounds | BTG INT LTD (GB) | 2006-07-19 | — | — | CN | disclosed |
| US-20060142286-A1 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2006-06-29 | — | — | US | disclosed |
| EP-1631557-A1 | CYCLIC HYDROXYLAMINE AS PSYCHOACTIVE COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 2006-03-08 | — | — | EP | disclosed |
| WO-2004111021-A1 | CYCLIC HYDROXYLAMINE AS PSYCHOACTIVE COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 2004-12-23 | — | — | WO | disclosed |
| WO-2004111021-A1 | CYCLIC HYDROXYLAMINE AS PSYCHOACTIVE COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015947-A1 | Cyclic hydroxylamine as psychoactive compounds | HTR1A, HTR1D, OPRM1 | NUDT1 1706/4885BACE1 3611/4885PIK3C3 4615/4885 |
| US-20090312329-A1 | Cyclic hydroxylamine as psychoactive compounds | HTR1A, HTR2C, OPRM1 | NUDT1 1491/4885BACE1 3466/4885PIK3C3 4498/4885 |
| US-20060142286-A1 | Cyclic hydroxylamine as psychoactive compounds | HTR1A, HTR2C, OPRM1 | NUDT1 1491/4885BACE1 3466/4885PIK3C3 4498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.