Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 4/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20240279 | 0.79 | LMNA (0.67) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20240298 | 0.78 | LMNA (0.55) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29960461 | 0.78 | LMNA (0.55) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4715538 | 0.78 | ALDH1A1 (0.55) | ALDH1A1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL9271359 | 0.78 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTNPSR1ERN1 | |
| SCHEMBL16294809 | 0.77 | LMNA (0.51) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4504197 | 0.77 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTNPSR1RAB9A | |
| SCHEMBL13574617 | 0.76 | SLC6A3 (0.55) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL644569 | 0.75 | MAPT (0.63) | ALDH1A1LMNAMAPTNPSR1ERN1 | |
| SCHEMBL3647722 | 0.75 | ALDH1A1 (0.53) | ALDH1A1MAPTERN1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267778-A1 | Diphenyl ether compound, process for producing the same, and use | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-10-21 | — | — | US | disclosed |
| EP-1661879-A1 | DIPHENYL ETHER COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267778-A1 | Diphenyl ether compound, process for producing the same, and use | PPARG, PPARD, PPARA | ALDH1A1 2015/4885LMNA 1343/4885CYP1A2 479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.