Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10167466 | 0.90 | HTT (0.38) | MEN1KMT2AMAPTHTTTP53 | |
| SCHEMBL353612 | 0.89 | MEN1 (0.35) | MEN1KMT2AMAPTHTTTP53 | |
| SCHEMBL10167510 | 0.86 | MAPT (0.43) | MEN1KMT2AMAPTHTTTP53 | |
| SCHEMBL10167492 | 0.82 | MAPT (0.36) | MAPTHTTTP53SMN1; SMN2KDM4E | |
| SCHEMBL354475 | 0.80 | HTT (0.40) | MEN1KMT2AHTTTP53SMN1; SMN2 | |
| SCHEMBL10167456 | 0.77 | ALDH1A1 (0.39) | MEN1KMT2AMAPTHTTTP53 | |
| SCHEMBL352691 | 0.76 | KMT2A (0.39) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL10167434 | 0.75 | ALDH1A1 (0.37) | MEN1KMT2AMAPTHTTTP53 | |
| SCHEMBL10167462 | 0.75 | TP53 (0.38) | MEN1KMT2AMAPTHTTTP53 | |
| SCHEMBL352076 | 0.75 | HTR2C (0.34) | MEN1KMT2AMAPTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064196-B1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2012-03-14 | — | — | EP | disclosed |