Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352456 | 0.86 | HCRTR1 (0.39) | MEN1KMT2AHCRTR1HCRTR2MAPT | |
| SCHEMBL10167466 | 0.84 | HTT (0.38) | MEN1KMT2AMAPTHTTTP53 | |
| SCHEMBL10167492 | 0.83 | MAPT (0.36) | HCRTR1HCRTR2MAPTHTTUSP30 | |
| SCHEMBL353134 | 0.83 | HCRTR1 (0.39) | MEN1KMT2AHCRTR1HCRTR2HTT | |
| SCHEMBL354766 | 0.82 | HCRTR1 (0.35) | HCRTR1HCRTR2TP53 | |
| SCHEMBL10167510 | 0.80 | MAPT (0.43) | MEN1KMT2AMAPTHTTTP53 | |
| SCHEMBL353355 | 0.79 | KMT2A (0.36) | MEN1KMT2AHCRTR1HCRTR2MAPT | |
| SCHEMBL354277 | 0.74 | HCRTR1 (0.35) | HCRTR1HCRTR2KDM4E | |
| SCHEMBL357050 | 0.72 | KDM4E (0.34) | MEN1KMT2AHCRTR1HCRTR2MAPT | |
| SCHEMBL10167456 | 0.72 | ALDH1A1 (0.39) | MEN1KMT2AMAPTHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064196-B1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2012-03-14 | — | — | EP | disclosed |