Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | RAD52 | P43351 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353134 | 0.89 | HCRTR1 (0.39) | HTTALDH1A1MEN1KMT2ARAD52 | |
| SCHEMBL10167509 | 0.84 | RAD52 (0.51) | HTTALDH1A1MEN1KMT2ARAD52 | |
| SCHEMBL352691 | 0.83 | KMT2A (0.39) | HTTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL10167495 | 0.81 | MEN1 (0.41) | HTTALDH1A1MEN1KMT2ARAD52 | |
| SCHEMBL351052 | 0.80 | MEN1 (0.42) | HTTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL353613 | 0.75 | MAPT (0.44) | HTTALDH1A1NPC1 | |
| SCHEMBL352076 | 0.75 | HTR2C (0.34) | MEN1KMT2AHPGDTP53NPC1 | |
| SCHEMBL353355 | 0.74 | KMT2A (0.36) | HTTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL352456 | 0.73 | HCRTR1 (0.39) | ALDH1A1MEN1KMT2ATSHRNPC1 | |
| SCHEMBL358113 | 0.72 | KMT2A (0.40) | HTTALDH1A1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064196-B1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2012-03-14 | — | — | EP | disclosed |