Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL358113 | 0.90 | KMT2A (0.40) | KMT2ASMN1; SMN2MEN1LMNAALDH1A1 | |
| SCHEMBL353355 | 0.90 | KMT2A (0.36) | KMT2ASMN1; SMN2MEN1LMNAALDH1A1 | |
| SCHEMBL10167584 | 0.87 | L3MBTL1 (0.42) | KMT2ASMN1; SMN2MEN1LMNAALDH1A1 | |
| SCHEMBL10167556 | 0.83 | KMT2A (0.35) | KMT2ASMN1; SMN2MEN1LMNAALDH1A1 | |
| SCHEMBL354475 | 0.83 | HTT (0.40) | KMT2ASMN1; SMN2MEN1LMNAALDH1A1 | |
| SCHEMBL353442 | 0.78 | LMNA (0.36) | KMT2ASMN1; SMN2MEN1LMNAALDH1A1 | |
| SCHEMBL351633 | 0.76 | KMT2A (0.40) | KMT2ASMN1; SMN2MEN1LMNAALDH1A1 | |
| SCHEMBL10167459 | 0.75 | TP53 (0.42) | KMT2ASMN1; SMN2MEN1LMNAALDH1A1 | |
| SCHEMBL353134 | 0.73 | HCRTR1 (0.39) | KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL10167578 | 0.72 | L3MBTL1 (0.42) | KMT2ASMN1; SMN2MEN1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064196-B1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2012-03-14 | — | — | EP | disclosed |