Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275863 | 0.79 | ALOX15 (0.47) | ALOX15ALDH1A1KCNH2TAAR1HTR1A | |
| SCHEMBL14035741 | 0.76 | ALOX15 (0.44) | ALOX15ALDH1A1KCNH2TAAR1HTR1A | |
| SCHEMBL15925068 | 0.76 | ALOX15 (0.44) | ALOX15KCNH2TAAR1HTR1AFDPS | |
| SCHEMBL14008876 | 0.76 | ALOX15 (0.41) | ALOX15TAAR1HTR1A | |
| SCHEMBL15639078 | 0.73 | LMNA (0.50) | ALDH1A1KMT2ALMNAL3MBTL1TAAR1 | |
| SCHEMBL10448525 | 0.71 | DBH (0.50) | ALOX15ALDH1A1POLBTSHR | |
| SCHEMBL31270697 | 0.71 | LMNA (0.74) | ALDH1A1POLBKMT2ALMNAL3MBTL1 | |
| SCHEMBL15013385 | 0.70 | ALOX15 (0.39) | ALOX15KCNH2TAAR1HTR1A | |
| SCHEMBL14321911 | 0.70 | — | — | |
| SCHEMBL4779659 | 0.69 | ALDH1A1 (0.72) | ALDH1A1POLBKMT2ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293919-B2 | Antibacterial sulfone and sulfoxide substituted heterocyclic urea compounds | CRESTONE, INC. (US) | 2012-10-23 | — | — | US | disclosed |
| US-20100286169-A1 | Antibacterial Sulfone and Sulfoxide Substituted Heterocyclic Urea Compounds | CRESTONE, INC. (US) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286169-A1 | Antibacterial Sulfone and Sulfoxide Substituted Heterocyclic Urea Compounds | TST, UMPS, UROD | ALOX15 4081/4885ALDH1A1 2644/4885POLB 1370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.