SCHEMBL728256

SCHEMBL728256

Cn1c2ccccc2c2cc(N)ccc21

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.66
KMT2A Q03164 4/20 0.66
KDM4E B2RXH2 4/20 0.66
MAPT P10636 4/20 0.66
ALDH1A1 P00352 3/20 0.66
HPGD P15428 3/20 0.66
HTT P42858 2/20 0.66
HSD17B10 Q99714 2/20 0.66
MAPK1 P28482 1/20 0.66
HBB P68871 1/20 0.66
TDP1 Q9NUW8 1/20 0.66
GPR3 P46089 1/20 0.64
L3MBTL1 Q9Y468 2/20 0.58
PABPC1 P11940 1/20 0.56
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
HCRTR1 O43613 1/20 0.50
POLB P06746 1/20 0.49
SIGMAR1 Q99720 1/20 0.49
TLR9 Q9NR96 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29565790 1.00 MEN1 (0.66) MEN1KMT2AKDM4EMAPTALDH1A1
SCHEMBL29433546 0.89 KDM4E (0.50) MEN1KMT2AKDM4EMAPTALDH1A1
SCHEMBL351390 0.89 KDM4E (0.50) MEN1KMT2AKDM4EMAPTALDH1A1
SCHEMBL3875050 0.88 GPR3 (0.64) MEN1KMT2AKDM4EMAPTALDH1A1
SCHEMBL28179893 0.85 NPC1 (0.71) MEN1KMT2AKDM4EMAPTALDH1A1
SCHEMBL22384864 0.85 GPR3 (0.55) MEN1KMT2AKDM4EMAPTALDH1A1
SCHEMBL22780595 0.82 ALDH1A1 (0.62) MEN1KMT2AKDM4EMAPTALDH1A1
SCHEMBL31135510 0.82 ALDH1A1 (0.62) MEN1KMT2AKDM4EMAPTALDH1A1
SCHEMBL3423941 0.81 GPR3 (0.80) MEN1KMT2AKDM4EMAPTALDH1A1
SCHEMBL11757062 0.80 KDM4E (0.76) MEN1KMT2AKDM4EMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3396028-B1 DIRECT ELECTROCHEMICAL SYNTHESIS OF DOPED CONDUCTIVE POLYMERS ON METAL ALLOYS BOEING CO (US) 2022-04-06 EP claimed
US-7211202-B2 Process to make a conductive composition of a fluorinated polymer which contains polyaniline ATOFINA (FR) 2007-05-01 US claimed
EP-1428857-B1 Process to make a conductive composition of a fluorinated polymer which contains polyaniline ARKEMA FRANCE (FR) 2007-01-31 EP claimed
EP-0161281-A4 STABILIZATION OF INDICATORS FOR DETECTING ENZYME ACTIVITY. IMMUNO CONCEPTS INC (US) 1987-04-28 EP claimed
EP-0161281-A1 STABILIZATION OF INDICATORS FOR DETECTING ENZYME ACTIVITY. IMMUNO CONCEPTS INC (US) 1985-11-21 EP claimed
WO-1985002018-A1 STABILIZATION OF INDICATORS FOR DETECTING ENZYME ACTIVITY IMMUNO CONCEPTS, INC. (US) 1985-05-09 WO claimed
US-20250369031-A1 METHODS OF DETERMINING CERULOPLASMIN ACTIVITY AND APPLICATIONS THEREOF ACADEMIA SINICA (TW) 2025-12-04 US disclosed
US-12371417-B2 Compounds with tubulin polymerisation inhibitory activity and immunomodulatory properties Universite Paris-Saclay (FR) 2025-07-29 US disclosed
WO-2023249941-A1 METHODS OF DETERMINING CERULOPLASMIN ACTIVITY AND APPLICATIONS THEREOF ACADEMIA SINICA (TW) 2023-12-28 WO disclosed
WO-2023249941-A1 METHODS OF DETERMINING CERULOPLASMIN ACTIVITY AND APPLICATIONS THEREOF ACADEMIA SINICA (TW) 2023-12-28 WO disclosed
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 US disclosed
US-20230203005-A1 COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES Universite Paris-Saclay (FR) 2023-06-29 US disclosed
US-11634405-B2 Compounds with tubulin polymerisation inhibitory activity and immunomodulatory properties UNIVERSITE PARIS-SACLAY PARC TECHNOLOGIQUE (FR) 2023-04-25 US disclosed
US-4526963-A Dioxazine pigments SANDOZ LTD. (CH) 1985-07-02 US disclosed
US-4061642-A AZO DYE INTERMEDIATES CASSELLA FARBWERKE MAINKUR AG (DT) 1977-12-06 US disclosed
US-3980659-A INSECTICIDES, INTERMEDIATES FOR AZO DYES CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-09-14 US disclosed
US-3956294-A AZO DYES, PESTICIDES, ANALEPTICS, ANALGESICS, DIURETICS CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-11 US disclosed
US-3954782-A 2,6-Hydrazino-3-pyridine carboxyamides CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-04 US disclosed
US-3947463-A Certain 2-amino-nicotinonitrile derivatives CASSELLA FARBWERKE MAINKUR AG (DT) 1976-03-30 US disclosed
US-3946024-A INTERMEDIATES FOR AZO DYES CASSELLA FARBWERKE MAINKUR AG (DT) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12371417-B2 Compounds with tubulin polymerisation inhibitory activity and immunomodulatory properties TUBB1, TUBB, TUBB3 MEN1 2528/4885KMT2A 3768/4885KDM4E 3840/4885
US-11634405-B2 Compounds with tubulin polymerisation inhibitory activity and immunomodulatory properties TUBB1, TUBB, TUBB3 MEN1 2528/4885KMT2A 3768/4885KDM4E 3840/4885
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes KCNQ2, KCNQ1, KCNQ4 MEN1 3802/4885KMT2A 1221/4885KDM4E 962/4885
US-20230203005-A1 COMPOUNDS WITH TUBULIN POLYMERISATION INHIBITORY ACTIVITY AND IMMUNOMODULATORY PROPERTIES TUBB1, TUBB, TUBB3 MEN1 2528/4885KMT2A 3768/4885KDM4E 3840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.