Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 2/20 | 0.43 |
| ▸ | PNP | P00491 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 10/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28333212 | 0.88 | ALDH1A1 (0.42) | POLGPNPPOLBPOLA1 | |
| SCHEMBL389888 | 0.86 | PNP (0.46) | POLGPNPPOLBPOLA1HPRT1 | |
| SCHEMBL28335557 | 0.85 | ALDH1A1 (0.44) | POLGPNPPOLBPOLA1 | |
| SCHEMBL76055 | 0.78 | POLG (0.62) | POLGPNPPOLBPOLA1HPRT1 | |
| SCHEMBL101894 | 0.76 | PNP (0.61) | POLGPNPPOLBPOLA1HPRT1 | |
| SCHEMBL1820814 | 0.74 | ALDH1A1 (0.49) | PNP | |
| SCHEMBL4957491 | 0.71 | PNP (0.39) | PNP | |
| SCHEMBL3085105 | 0.70 | PNP (0.38) | PNP | |
| SCHEMBL443837 | 0.69 | POLG (0.47) | POLGPNPPOLBPOLA1HPRT1 | |
| SCHEMBL16180228 | 0.69 | POLG (0.47) | POLGPNPPOLBPOLA1HPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317005-A1 | Modified Nucleotides and Methods for Making and Use Same | Life Technologies Corporation (US) | 2010-12-16 | — | — | US | claimed |