SCHEMBL3515970

SCHEMBL3515970

O=C(O)CCC(S)CCS

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 7/20 0.58
ANPEP P15144 4/20 0.58
ENPEP Q07075 4/20 0.58
TET2 Q6N021 3/20 0.42
KDM4A O75164 2/20 0.42
KDM4C Q9H3R0 2/20 0.42
KDM2A Q9Y2K7 2/20 0.42
ACE P12821 1/20 0.42
TET3 O43151 1/20 0.42
GABRP O00591 2/20 0.41
GABRD O14764 2/20 0.41
GABRA1 P14867 2/20 0.41
GABRB1 P18505 2/20 0.41
GABRG2 P18507 2/20 0.41
GABRB3 P28472 2/20 0.41
GABRA5 P31644 2/20 0.41
GABRA3 P34903 2/20 0.41
GABRA2 P47869 2/20 0.41
GABRB2 P47870 2/20 0.41
GABRA4 P48169 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19182605 0.87 FOLH1 (0.59) FOLH1ANPEPENPEPTET2KDM4A
SCHEMBL3521389 0.86 FOLH1 (0.52) FOLH1ANPEPENPEP
SCHEMBL3517277 0.86 FOLH1 (0.61) FOLH1ANPEPENPEPTET2KDM4A
Dihydrolipoic Acid SCHEMBL19773 0.84 FOLH1 (0.56) FOLH1ANPEPENPEP
SCHEMBL3515557 0.84 FOLH1 (0.62) FOLH1ANPEPENPEPACE
Dihydrolipoic Acid SCHEMBL867951 0.84 FOLH1 (0.56) FOLH1ANPEPENPEP
Dihydrolipoic Acid SCHEMBL1115003 0.84 FOLH1 (0.56) FOLH1ANPEPENPEP
Dihydrolipoic Acid SCHEMBL618576 0.84 FOLH1 (0.56) FOLH1ANPEPENPEP
Dihydrolipoic Acid SCHEMBL2578740 0.82 FOLH1 (0.54) FOLH1ANPEPENPEP
SCHEMBL6809842 0.82 GSTK1 (0.57) FOLH1ANPEPENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020007822-A1 BISMUTH METALLIC (0) NANOPARTICLES, PROCESS OF MANUFACTURING AND USES THEREOF CONSERVATOIRE NATIONAL DES ARTS ET METIERS (CNAM) (FR) 2020-01-09 WO disclosed
US-20100190902-A1 ALKYLTIN SULFANYL ESTER THIOLS CHEMTURA CORPORATION (US) 2010-07-29 US disclosed
US-20040133938-A1 Use of lipoic acid in plant culture media MONSANTO TECHNOLOGY LLC 2004-07-08 US disclosed
CN-1208035-A Dithiolan derivatives, their preparation and their therapeutic effect SANKYO CO (JP) 1999-02-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100190902-A1 ALKYLTIN SULFANYL ESTER THIOLS SULT1E1, SULT1A1, TST FOLH1 4882/4885ANPEP 3836/4885ENPEP 3338/4885
US-20040133938-A1 Use of lipoic acid in plant culture media TTPA, TST, LRAT FOLH1 2347/4885ANPEP 3988/4885ENPEP 2850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.