Phthalic Acid

Phthalic Acid

SCHEMBL7201091

C=CCC(=O)O.CC=CC(=O)O.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
ALOX15 P16050 1/20 0.44
KMT2A Q03164 2/20 0.40
AKR1C3 P42330 2/20 0.37
CYP3A4 P08684 1/20 0.37
NR4A1 P22736 2/20 0.36
NR4A2 P43354 1/20 0.36
NR4A3 Q92570 1/20 0.36
KDM4E B2RXH2 2/20 0.36
HPGD P15428 2/20 0.36
MYC P01106 2/20 0.36
CDC25B P30305 1/20 0.36
CYP1A2 P05177 1/20 0.36
MAPT P10636 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
HMGB1 P09429 1/20 0.35
CA4 P22748 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL35170 0.87 ALDH1A1 (0.58) ALDH1A1ALOX15KMT2AAKR1C3CYP3A4
Crotonic Acid SCHEMBL1618932 0.83 ALOX15 (0.36) ALDH1A1ALOX15MAPTHSD17B10TDP1
Crotonic Acid SCHEMBL2406680 0.83 ALOX15 (0.36) ALDH1A1ALOX15MAPTHSD17B10TDP1
Crotonic Acid SCHEMBL11525007 0.83 ALOX15 (0.36) ALDH1A1ALOX15MAPTHSD17B10TDP1
Phthalic Acid SCHEMBL11745850 0.79 ALDH1A1 (0.58) ALDH1A1ALOX15KMT2AAKR1C3CYP3A4
Phthalic Acid SCHEMBL11745843 0.79 ALDH1A1 (0.58) ALDH1A1ALOX15KMT2AAKR1C3CYP3A4
Crotonic Acid SCHEMBL27396103 0.78 FFAR3 (0.40) ALDH1A1ALOX15MAPT
Phthalic Acid SCHEMBL1325027 0.78 ALDH1A1 (0.47) ALDH1A1ALOX15KMT2AAKR1C3CYP3A4
Salicylic Acid SCHEMBL2040340 0.77 ALDH1A1 (0.64) ALDH1A1ALOX15KMT2ACYP3A4KDM4E
Phthalic Acid SCHEMBL9241582 0.76 ALDH1A1 (0.54) ALDH1A1ALOX15KMT2AAKR1C3NR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1985003437-A1 DIFFUSION COATED MULTIPLE-UNITS DOSAGE FORM A/S ALFRED BENZON (DK) 1985-08-15 WO claimed
US-6599529-B1 Fast acting; sustained release NYCOMED DANMARK A/S (DK) 2003-07-29 US disclosed